Scientist, Flow Cytometry (non-PhD)
Pfizer’s purpose is to deliver breakthroughs that change patients’ lives. Research and Development is at the heart of fulfilling Pfizer’s purpose as we work to translate advanced science and technologies into the therapies and vaccines that matter most. Whether you are in the discovery sciences, ensuring drug safety and efficacy or supporting clinical trials, you will apply cutting edge design and process development capabilities to accelerate and bring the best in class medicines to patients around the world.What You Will Achieve
As a Scientist, you will be at the center of our operations and you’ll find that everything we do, every day, is in line with an unwavering commitment to quality. You will be part of a team that is addressing the critical task of rejuvenating our pipeline with innovative, differentiated First-In-Class/ Only-In-Class programs in the years to come. This will be addressed by generation of strong data packages from target hypotheses derived from academic outreach and initiatives. You will be an essential member of this team and creatively design and execute key experiments to address the basic and translational biology of novel drug targets, their molecular pathways, and their connection to human disease. You will support projects in one or more therapeutic areas of interest to Pfizer including Immunology, Oncology, Immuno-Oncology, etc.
With your deep knowledge in the discipline, you will be an active team member who influences at the project team level. You will be using your scientific judgment to adapt standard methods and techniques by applying prior work experience and consulting others. Your ability to plan will help in preparing short-term work activities on projects. Your creativity in developing novel processes and new ideas will be used frequently. You will undertake mentoring activities to guide your team members.
It is your innovative scientific temperament that will help in making Pfizer ready to achieve new milestones and help patients across the globe.How You Will Achieve It
- Contribute to achievement of goals of the team and influence at the work group/project team level.
- Apply technical skills and functional knowledge to projects/ assignments within own work group/ project team independently and proactively.
- Perform laboratory experiments to help establish robust disease biology, biochemical and cell-based compound screening assays and carry out in vivo evaluation across a broad array of target classes for the project teams.
- Prepare and present experimental results to project teams.
- Comply with all safety training and good laboratory practices.
- Bachelor's Degree
- 6+ years of experience operating and maintaining flow cytometers and designing flow cytometry experiments
- 2+ years experience with high-speed cell sorting
- Experience in immune cell isolation and characterization using multi-color flow cytometry
- Strong background in immunology, microbiology (bacteriology or virology)
- Ability to use appropriate software to perform analysis of data
- Excellent organization and planning skills, the ability to work in a fast-paced environment independently or as part of a team, strong motivation with a dedicated work ethic
- Excellent verbal and written communication skills
- Master's degree and 4+ years of relevant experience
- Experience designing and running Cytof/Helios experiments
- Experience in a shared resource lab environment
- Experience in mouse solid tumor processing
- Knowledge in multi-parameter flow cytometry analysis of tumor infiltrating immune cells, especially utilizing large antibody panels
- Experience with multiple flow cytometry platforms, including various BD FACSDiva instrumentation, BC Cytoflex, Sartorius iQue, Cytek Aurora, Sony analyzers and sorters.
- Ability to travel short distances between buildings
- Remain sitting or standing for long periods of time to work in the lab, on the computer, telephone, or other equipment
NON-STANDARD WORK SCHEDULE, TRAVEL OR ENVIRONMENT REQUIREMENTS
- Occasional non-standard work hours