Breakthrough Fellowship Program – Global Science – Quantitative Systems & Medical Decision Making

Cambridge, MA
Oct 05, 2021
Required Education
Bachelors Degree
Position Type
Full time

Breakthrough Fellowship Program – Global Science – Quantitative Systems & Medical Decision Making

This program is designed to enhance our pipeline of diverse talent of leaders. The Breakthrough Fellowship Program, first-of-its-kind, works to advance students and early career colleagues of Black/African American, Latino/Hispanic and Native American descent with a goal of developing 100 fellows by 2025. One of Pfizer’s Bold Moves is to create a workplace for all, and we are committed to increasing diversity by fostering a more inclusive workplace.  Every Pfizer ‘Breakthrough’ program is designed to cultivate a pipeline of diverse talent.  Everything we do is driven by our purpose. 

Successful candidates in the Breakthrough Fellowship Program participate in a 10-week summer internship and intend to pursue a Master of Science (or equivalent) degree in a quantitative discipline, Masters of Statistics or other graduate degree that aligns to the program.

There are 2 openings in the Global Sciences business to join the Breakthrough Fellowship Program. Apply to this requisition if you are interested in one or more of these following positions:

Quantitative Systems Pharmacology - The Early Clinical Development Quantitative Systems Pharmacology group (ECD QSP) is a mathematical modeling and simulation team focused on developing tools to simulate diseases and clinical trials. It is well situated to provide a comprehensive experience of working in Pfizer Worldwide Research and Development and Medical and beyond. The group is involved with research and development programs from inception through to Phase III. ECD QSP is well integrated into research at Pfizer’s Kendall Square (KSQ) site in Cambridge, MA, and works with multiple research units and functions at Pfizer (including Biomedicines and Medicines Design, ECD Precision Medicine, Statistics, Digital, and Global Product Development).

Medical Decision Making (MDM) Research – The Breakthrough Fellow will work closely with the Lifecycle Benefit Risk Expert, Medical Decision Analyst, Patient Preference Expert, and other Global Medical Impact Assessment (GMIA) team members to support and coordinate quantitative benefit-risk (qBR) assessments for decision-making for marketed and investigational products across Global Business Units. The research associate will work with GMIA and cross-functional asset teams to manage qBR projects. This selected candidate will prepare data for analytics by identifying, extracting and collating relevant research documents and publications, and conduct literature searches and reviews as required. The research associate will also provide project management support for qBR assessments, decision analyses, including decision tree construction, benefit-risk model development, predictive benefit risk modeling, literature review and risk communication.

Required Background: 

An undergraduate in a 4-year program pursuing a BS degree December 2022 or Spring 2023 in Mathematics, Physics, Engineering. Interest or background in applications to biological systems.

Min GPA 3.0


For the Medical Decision-Making Position - Basic coding skills (familiarity with MATLAB, C/C++, or julia preferred)

  • Prior classes covering ‘ordinary differential equations’ (ODEs). Familiarity with how ODEs might be used to model biological systems (through coursework or otherwise), and numerical solution of ODEs, is preferred

  • Keen interest in learning new areas of biology, new mathematical and computational techniques, and about the drug development process

Demonstrative ability OR Enthusiasm to Learn:

  • Basic to advanced mathematical modeling of biological systems

  • The breadth of the drug discovery process at Pfizer through technical meetings and seminars 

  • Working in a team of experts in the application of mechanistic systems models to enhance drug development and discovery

  • Interfacing with multi-disciplinary teams consisting of pharmacologists, biologists, clinicians, statisticians and mathematical modelers at Pfizer

  • Developing and applying mechanistic mathematical models to quantitatively address critical uncertainties in drug discovery and development

  • Presenting work at internal seminars and external conferences, as well as contributing to peer-reviewed publication of the model

Work Authorization

Applicants must be immediately authorized to work in the U.S.  Work visa sponsorship not available for this opportunity. Pfizer is an equal opportunity and E-Verify employer.

Posting details - This position will close Oct 31, 2021

Location - New York City NY, Kendall Square MA, Collegeville PA or remote/virtual should the 2022 summer program be held virtually.

Pfizer requires all U.S. new hires to be fully vaccinated for COVID-19 prior to the first date of employment.  As required by applicable law, Pfizer will consider requests for Reasonable Accommodations.

Sunshine Act

Pfizer reports payments and other transfers of value to health care providers as required by federal and state transparency laws and implementing regulations.  These laws and regulations require Pfizer to provide government agencies with information such as a health care provider’s name, address and the type of payments or other value received, generally for public disclosure.  Subject to further legal review and statutory or regulatory clarification, which Pfizer intends to pursue, reimbursement of recruiting expenses for licensed physicians may constitute a reportable transfer of value under the federal transparency law commonly known as the Sunshine Act.  Therefore, if you are a licensed physician who incurs recruiting expenses as a result of interviewing with Pfizer that we pay or reimburse, your name, address and the amount of payments made currently will be reported to the government.  If you have questions regarding this matter, please do not hesitate to contact your Talent Acquisition representative.

EEO & Employment Eligibility

Pfizer is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status.  Pfizer also complies with all applicable national, state and local laws governing nondiscrimination in employment as well as work authorization and employment eligibility verification requirements of the Immigration and Nationality Act and IRCA.  Pfizer is an E-Verify employer.

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