Scientist (non-PhD), Tumor Immunogenicity
Pfizer’s purpose is to deliver breakthroughs that change patients’ lives. Research and Development is at the heart of fulfilling Pfizer’s purpose as we work to translate advanced science and technologies into the therapies and vaccines that matter most. Whether you are in the discovery sciences, ensuring drug safety and efficacy or supporting clinical trials, you will apply cutting edge design and process development capabilities to accelerate and bring the best in class medicines to patients around the world.What You Will Achieve
Pfizer Cancer Immunology Discovery (CID) is within the Oncology division of Pfizer Worldwide Research & Development in La Jolla, CA. CID is dedicated to developing new protein and small molecule therapeutics to improve human life by redirecting the immune system against cancer by leveraging cytokine biology. CID researchers apply the latest scientific knowledge and novel approaches to discover truly innovative Immuno-Oncology therapeutics.
We are seeking to hire a non-PhD Scientist for the Tumor Immunogenicity CID group.
Execution of cell-based functional and biochemical assays to select candidate molecules for clinical development.
Planning and execution of in vivo mouse studies and ex vivo functional assessments, such as, multi-color flow cytometry, gene expression analyses, and primary cell culture.
Analyze, organize, and present results in small and large group meetings.
Read relevant scientific literature to aid in experimental design.
Contribute to a dynamic, exciting culture that embraces teamwork and innovation.
B.S. degree with 6+ years’ experience.
Experience in the fields of immunology or cell biology.
Ability to plan and execute in vitro and/or in vivo/ex vivo experiments with minimal supervision.
Expertise in standard immunologic techniques (e.g. ELISA or FACS) and willingness to develop skills in a broad set of cutting-edge techniques.
Excellent organization and planning skills, the ability to work in a fast-paced environment independently or as part of a team, good verbal and written communication, and strong motivation with a dedicated work ethic.
M.S. degree with 4+ years of experience.
Technical expertise with immune cell-based functional assays (e.g. activation, differentiation, proliferation, and suppression assays by using monocyte/ macrophages, T-cells, or dendritic cells).
Immune phenotyping tumor associated immune cells from primary mouse tissue samples by high-parameter flow cytometry.
Experience in CRISPR technology and lentiviral transduction.
Experience with various murine tumor and/or infectious disease models.
Experience with human PBMC and mammalian cell culture.