Cell Support Laboratory Manager

PRIMARY RESPONSIBILITIES:

• Supervise, train, mentor and develop assigned staff
• Ensure the laboratory procedures are performed with strict adherence to SOPs
• Review procedure worksheets and ensuring QC procedures are performed and documented according to SOPs, reviews QC procedures
• Assign all technologist daily workload and maintaining on-call schedule
• Supervise processing, cryopreservation and storage of tumor cells. Responsible for maintaining adequate inventory of supplies and reagents utilized in the cell culture laboratory
• Perform mammalian tissue culture on mouse and human cell lines as well as primary immune cells. Thaw and expand cells for large scale in vivo studies
• Cell culture media preparation, cell banking and testing
• Perform calculations necessary for determining cell doubling time, cell concentration, seeding density, molarity, etc
• Assist in writing, revising, and improving project records, cell culture records and logs, SOPs, training materials, protocols, reports, and other required documentation
• Troubleshoot technical process, cell culture issues, and equipment problems
• Work in a dynamic, team-based environment and coordinate with other departments. Collaborate with other departments such as in vivo, biomarker, quality, logistics, in order to support the manufacturing activities
• The responsibilities listed are a general overview of the position and additional duties may be assigned

EDUCATION, KNOWLEDGE, AND EXPERIENCE REQUIREMENTS:

• Adherence to Quality System Bachelor's degree in Biology, Biochemistry or related area with 5+ years, or Master degree with 3+ years experience in cell culture
• Experience with people management preferred

SKILL REQUIREMENTS:

• Comfortable with maintaining a variety of cell lines at once
• Able to identify and troubleshoot issues with cell cultures, for example, signs of over trypsinization, under- or over seeding, contamination (from bacteria, fungus, or even other cell lines), senescence
• Experience with large scale cell culture is a huge plus
• Comfortable with calculations necessary for determining cell doubling time, cell concentration, seeding density, molarity, etc.
• Comfortable using computers, including an advanced knowledge of the Microsoft Office suite, e-mail, and internet
• Exceptional organizational, time- management, and prioritization skills
• Able to multi-task with a high degree of professionalism and diplomacy
• Willing and able to work within a Quality System with oversight by QA and other regulatory bodies
• Able to troubleshoot effectively and solve scientific problems with moderate supervision
• Able to find, read, and understand relevant scientific literature
• Willing and able to work under the pressure of deadlines and find solutions to meet timelines
• Able to work across teams by being a flexible team player
• Strong communication and interpersonal skills

WORKING CONDITIONS and PHYSICAL REQUIREMENTS:

• Sitting for long periods of time
• Prolonged computer usage
• Able to lift up to 30lbs
• Frequently required to use repetitive hand/wrist/arm motion
• BSL-2 Lab Environment
• Normal office environment