Senior Scientist, Machine Learning, Protein Engineering

Location
Redwood City, California
Posted
Sep 29, 2021
Ref
R1543481
Required Education
Doctorate/PHD/MD
Position Type
Full time

At Bristol Myers Squibb, we are inspired by a single vision transforming patients lives through science.In oncology, hematology, immunology and cardiovascular disease and one of the most diverse and promising pipelines in the industry each of our passionate colleagues contribute to innovations that drive meaningful change. We bring a human touch to every treatment we pioneer. Join us and make a difference.

Job Description:

We are seeking a skilled and enthusiastic computational scientist to join the Protein Engineering group. The group uses computational and experimental techniques to develop and modify novel antibody-based biotherapeutics to drive specific responses in disease states, in close collaboration with other protein and immunology scientists. The candidate will use their expertise to create and implement machine learning models to generate and modify therapeutic-candidate molecules with optimized characteristics, for further testing and development.

Specific Responsibilities:
  • Lead computational protein engineering efforts to create and optimize machine learning models for novel antibody-based biotherapeutic drug discovery.

  • Process datasets (experimental, sequence, and structural) and create frameworks for machine learning models for generating or modifying macromolecules with predicted characteristics.

  • Produce interpretable results that can be used for subsequent experimental design and testing.

  • Perform computational design and modeling to assess and create molecules with attention to biological function.

  • Evaluate new methodologies and their applicability to molecular design.

  • Interpret results and present to team members, under team timelines.

  • Contribute to patents and publications.

Requirements:
  • Ph.D. in structural biology, computational biology, computer science, or similar fields with 0-2 years of industry experience.

  • Programming experience in Python and/or R for data analytics and visualization.

  • Machine Learning / Deep Learning experience (Pytorch, TensorFlow, Scikit-learn, or similar) applied to biological problems.

  • Understanding of the sequence and structure of proteins and bioinformatics tools utilized in analyzing sets of related molecules.

  • Ability to creatively contribute to multidisciplinary biologics discovery teams.

Bristol Myers Squibb recognizes the importance of balance and flexibility in our work environment. We offer a wide variety of competitive benefits, services and programs that provide our employees the resources to pursue their goals, both at work and in their personal lives.

Around the world, we are passionate about making an impact on the lives of patients with serious diseases. Empowered to apply our individual talents and diverse perspectives in an inclusive culture, our shared values of passion, innovation, urgency, accountability, inclusion and integrity bring out the highest potential of each of our colleagues.

Bristol Myers Squibb recognizes the importance of balance and flexibility in our work environment. We offer a wide variety of competitive benefits, services and programs that provide our employees with the resources to pursue their goals, both at work and in their personal lives.

Physical presence at the BMS worksite or physical presence in the field is an essential job function of this role which the Company deems critical to collaboration, innovation, productivity, employee well-being and engagement, and enhances the Company culture.

To protect the safety of our workforce, customers, patients and communities, the policy of the Company requires all employees and workers in the U.S. and Puerto Rico to be fully vaccinated against COVID-19, unless they have received an exception based on an approved request for a medical or religious reasonable accommodation. Therefore, all BMS applicants seeking a role located in the U.S. and Puerto Rico must confirm that they have already received or are willing to receive the full COVID-19 vaccination by their start date as a qualification of the role and condition of employment. This requirement is subject to state and local law restrictions and may not be applicable to employees working in certain jurisdictions such as Montana. This requirement is also subject to discussions with collective bargaining representatives in the U.S.

Our company is committed to ensuring that people with disabilities can excel through a transparent recruitment process, reasonable workplace adjustments and ongoing support in their roles. Applicants can request an approval of accommodation prior to accepting a job offer. If you require reasonable accommodation in completing this application or if you are applying to a role based in the U.S. or Puerto Rico and you believe that you are unable to receive a COVID-19 vaccine due to a medical condition or sincerely held religious belief, during or any part of the recruitment process, please direct your inquiries to adastaffingsupport@bms.com. Visit careers.bms.com/eeo-accessibility to access our complete Equal Employment Opportunity statement.

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