Associate Scientist - Immunology
We are seeking an associate scientist with a strong background in immunology to join the Bispecific Antibodies group. The successful candidates will work closely with a talented team of protein engineers to develop novel immunocytokine and antibody-based therapeutics for cancer immunotherapy. Your primary responsibility is to design and perform preclinical in vivo studies to evaluate the efficacy and explore the mechanism of action of our novel immune modulatory therapeutics.
As an associate scientist, a typical day may include the following:
- Design and perform in vivo anti-tumor efficacy studies in both immunodeficient and immune competent mouse models, including dosing (IP, IV, SC) and tumor growth monitoring
- Design complex flow cytometry staining panels and perform flow analysis on immune cells, tumors, and tissues isolated from in vivo tumor studies
- Perform in vitro/ex vivo functional assays with primary human and murine immune cells (signaling, cell proliferation, cytotoxicity)
- Independently conduct data analysis and troubleshooting
- Maintain complete, accurate, and timely documentation of experimental procedures and results
- Present data at group and inter-departmental meetings
- Author documents for regulatory filings, patent applications, and scientific journal publications
This role may be for you if:
- You thrive in a creative, flexible, fast-paced collaborative team environment
- You have excellent communication, documentation and problem-solving skills
- You are keen on working in a cutting-edge environment to develop novel therapeutics
- You constantly look to expand your area of expertise
To be considered for this position, you must have a PhD and 0-2 years of post-doctoral experience in immunology, immuno-oncology or related fields with first author publications. Extensive knowledge and expertise in immunology, in vivo mouse techniques and complex multiparameter flow-cytometry is required. Experience with tumor modeling in mice is highly desirable. Additional experience with molecular biology and biochemistry techniques is a plus.