Skip to main content

This job has expired

You will need to login before you can apply for a job.

Senior Scientist, Bioassay Development Lead

Employer
Bolt Biotherapeutics
Location
Redwood City, CA
Start date
Sep 18, 2021

View more

Discipline
Science/R&D, Biotechnology
Required Education
Associate Degree
Position Type
Full time
Hotbed
Biotech Bay

Job Details

Senior Scientist, Bioassay Development Lead

The Position:

We are seeking an experienced scientist to build and lead Bolt’s CMC bioassay function. You will be responsible for development and optimization of cell-based and target-binding potency assays to support the development and characterization of Bolt’s Boltbody™ Immune-stimulating Antibody Conjugates (ISAC). You will provide scientific leadership and act as the subject matter expert for the CMC team. You will build a laboratory infrastructure and recruit, develop, mentor, and manage a team of research associates and/or scientists. This newly created position reports directly to the Head of Analytical Development.

About You:

You will have a Ph.D. degree in Biology, Cell Biology, Biochemistry, or related field, with at least 8 years’ experience (BS/MS degree with extensive industrial experience will also be considered) preferably in biotech or pharma industry with primary focus on biologics. In depth knowledge of understanding the mechanism of action (MoA) of biologics and experience in design, and development of MoA reflective bioassays using cell based and ELISA assays are required. Extensive experience in cell culture, cell line development is required. Experience in immunology and myeloid activation is highly desirable. Knowledge of FDA, cGMP, and ICH regulatory requirements in the context of bioassay development and qualification is required. Experience and knowledge of QC and GMP regulations is required. Experience with writing SOPs, training, and method transfers. Experience supporting Regulatory filings and writing INDs is a plus. Ability to multitask and meet deadlines in a fast-paced environment. Ability to think critically and demonstrate troubleshooting and problem-solving skills. Team player, good interpersonal and organizational skills. Excellent written and oral communication skills is required. The level of this position will be based on the final candidate’s qualification.

Who We Are:

Bolt Biotherapeutics, based in the San Francisco Bay Area, is a clinical-stage biotechnology company developing Boltbody™ Immune-stimulating Antibody Conjugates (ISACs), a new class of immuno-oncology therapeutics that have eliminated tumors following systemic administration in preclinical studies while also developing immunological memory, which may lead to more durable clinical responses for patients. This is a unique opportunity to join and build, with like-minded colleagues, a company that will transform the lives of individuals with cancers.

We are an Equal Opportunity Employer offering a competitive salary and benefits package.

Company

Bolt Biotherapeutics was founded in 2015 by Dr. Edgar G. Engleman of Stanford University to expand upon his pioneering work in cancer immunotherapeutics and myeloid biology. Bolt is based in the San Francisco Bay area.

Bolt’s highly qualified management team includes experienced leaders in immuno-oncology drug discovery, development and commercialization. Our goal is to leverage our myeloid biology expertise to discover, develop and commercialize transformative treatments to address key unmet medical needs for patients with cancer.

Company info
Website
Phone
(650) 665-9295
Location
900 Chesapeake Drive
Redwood City
CA
94063
US

Get job alerts

Create a job alert and receive personalized job recommendations straight to your inbox.

Create alert