Senior Process Development Associate
At SAB Biotherapeutics (SAB), we’re using the sophistication of science and genius of nature to change the landscape of human health. Our team of scientists, researchers and professionals has made it their life's work–with technology and tenacity–to pioneer a new powerful platform to make an impact that’s global + personal. Through advanced genetic engineering and antibody science, we are dedicated to advancing a new class of immunotherapies, leveraging the native human immune response, with first-in-class and best-in-class potential across broad therapeutic categories including autoimmune, inflammation, infectious disease and immune-oncology. SAB-185, is among the elite therapy candidates for COVID-19, advancing with Operation Warp Speed. As true innovation, our novel platform is also being developed in a rapid response capacity for future pandemic response.
The senior process development and purification associate is primarily responsible for development processes and maintenance of facilities and equipment in the PDP laboratory and the BSL2 laboratory.
Essential Duties and Responsibilities:
Responsibilities include but are not limited to:
- Perform protein purification on a bench scale
- Perform purification needs for reagent antigen production in BSL2
- Create purification methods in chromatography software programs
- Help train all associates in purification activities as needed
- Maintaining accurate records of purifications
- Write and update related SOPs, records, protocols, and development reports
- Work with Supervisor to plan and execute new projects as assigned to meet timelines
- Ability to optimize current purification methods and protocols for increased yield and purity
- Able to lead and assist research associates in purification activities when needed
- Maintaining all equipment used in the PDP department
- Maintain facilities, including regular laboratory areas and BSL2 laboratory
- Maintain a clean and safe lab environment
- Responsible for general laboratory ordering, maintaining, sample tracking
- Assist others in areas when needed.
To perform this job successfully, an individual must be able to perform each essential duty satisfactorily. The requirements listed below are representative of the knowledge, skill, and/or ability required.
Education, Experience and Certifications:
- Master’s degree and 1 year of experience OR
- Bachelor’s degree and 5 years of experience
- Certification in Quality by Design, preferred
- Certification in risk analysis, preferred
- Previous work with chromatography software, such as Cytiva UNICORN preferred
- Some computer programming knowledge is helpful
- Strong time management and organizational skills
- Critical thinker who can analyze and interpret data
- Ability to manage and complete projects as assigned
- Ability to work independently with minimal supervision
- Passion for continuous improvement
- Able to collaborate and work with people from different departments
Individual should possess strong communication skills and proficiency in Microsoft Office software (Word, Excel, PowerPoint, and Outlook) as well as the ability to effectively present information in one-on-one and small groups.
Basic mathematical skills to consist of addition, subtraction, multiplication, and division. Able to calculate dilutions and molarity.
While performing the duties of this job, the employee is regularly required to walk, stand, and sit. The employee must be able to move up to 100 pounds. Specific vision abilities required by this individual include close vision, peripheral vision, and the ability to adjust focus. The employee will view a computer monitor for long periods of time.
Physical Requirements/Working Conditions: Job requires good physical mobility. Ability to move over 100 pounds by mechanical means. Be able to sit for extended periods of time. Able to wear aseptic gowning for extended periods of time.
Duties will be performed in normal laboratory, ISO 7 environment, and BSL2 laboratory settings. Work in aseptic setting, ISO5 environment, from time to time.
The employer will make reasonable accommodations in compliance with the Americans with Disabilities Act of 1990.