Sr. Research Associate I

Position Summary

This position is responsible for cloning antigens and antibody variants and using phage display for candidate discovery and optimization for our antibody discovery programs.

Essential Functions

• Perform cloning methods, PCR methodologies, and vector and primer design
• Perform PCR, DNA mini-, midi-, maxi-prepping procedures
• Analyze DNA sequences
• Learn phage display, build antibody libraries, and screen for high affinity binders by ELISA
• Maintain and archive DNA clones, and bacterial glycerol stocks
• Organize, summarize and present data and results at department and project team meetings
• Assist/mentor junior, and new, laboratory personnel
• Develop an expanding technical and theoretical knowledge base in molecular biology with a growing understanding of the scientific literature in relevant areas of research
• Maintain a detailed and well organized record of experiments in an electronic notebook
• Maintain familiarity with literature to propose and implement improved procedures and protocols, and to aid in problem solving
• May prepare technical reports, summaries and detailed protocols, and contribute to journal articles and company reports as requested
• Follow and adhere to SOPs and laboratory safety regulations

Knowledge Requirements

• Practical knowledge of protein expression vectors (promoter, transcriptional signals, etc.) and have the ability to analyze DNA and protein sequences
• Proficiency working with DNA analysis software programs such as Sequencher, DNAStar or their equivalent, and with Microsoft Office (Word, Excel, Powerpoint)
• Ability to recognize when it is appropriate and necessary to modify a standard procedure or protocol
• Ability to possess a general understanding of own role and tasks, as well as the role of others in relation to the project as a whole

Personal Competencies

• Ability to communicate clearly, and to report and present experimental results and analysis to company colleagues
• Effective interpersonal skills, including excellent written and oral communication skills
• Ability to multi-task, organize multiple assignments, and work on several projects simultaneously while adhering to deadlines
• Ability to work effectively as a team player in a complex, changing environment
• Self-motivated, independent, and results-oriented
• Team player, intensely committed to success and getting the job done well in a highly dynamic environment
• Ability to work independently while also willing to follow protocols
• Strong analytical and organizational skills, with high attention to details

Work Environment

• Position may require occasional evening and/or weekend commitment
• Position may require working with biological and/or chemical hazards
• Position might require lifting up to 20 pounds

Education & Experience

• BA/BS in Molecular Biology or related scientific field, and 5+ years related experience, or MA/MS and 3+ years related experience
• Experience with standard molecular biology techniques
• Expertise in cloning and PCR methodologies, including vector and primer design
• Experience with phage display screening methodologies is preferred but not required
• Experience in industry is a plus

All qualified applicants will receive consideration for employment without regard to race, color, sex, sexual orientation, gender identity, religion, national origin, disability, veteran status, age, marital status, pregnancy, genetic information, or other legally protected status.