Scientist, Flow Cytometry

About the role

Sana Biotechnology is looking to expand our team with hard-working individuals who believe in the potential of engineered cells as medicines, have the vision to do creative things, and the determination to execute that vision. We are looking for a highly motivated Scientist/Senior Scientist with a passion for producing high quality data to expand our flow cytometry analytical capacity at Sana Biotechnology. You will leverage your technical expertise in flow cytometry by creating streamlined workflow solutions and collaborating with internal stakeholders and external vendors to drive the evaluation and implementation of a new automated flow cytometry data analysis pipeline. In addition, you will join an innovative , multi-disciplinary team and contribute to new flow cytometry method development, optimization, analytical testing, and technical data review to support company objectives . This is a cross-functional position in Analytical Development that will interface with peers in Research, Tech Sciences, Development Sciences, Process Development, and Quality Control. You will report to the Principal Scientist, Analytical Development.

What you'll do

• Lead the technical evaluation and implementation of an automated flow data analysis pipeline for analytical testing to improve analysis throughput and decrease turnaround time
• Participate in the technical review of analytical data generated from complex multi-color flow panels and provide other subject matter advice to teams on data analysis
• Serve as a subject matter expert in flow cytometry method development for use in both regulated (e.g. lot release, in-process, and stability testing) and unregulated environments (e.g. characterization and high throughput screening)
• Provide analytical support to Process Development and assist in tech transfer internally and externally in support of GMP manufacturing
• Author and revise analytical test methods and reports
• Maintain flow cytometry capabilities to relevant regulatory standards as needed and contribute to flow cytometry best practices

What we're looking for

• Ph.D. in Cell Biology, Immunology, or a related scientific discipline with up to 2+ years of academic or industry experience (Scientist level), or
• Ph.D. in Cell Biology, Immunology, or a related scientific discipline with 5+ years of academic or industry experience (Senior Scientist level)
• Expert knowledge of multi-color flow cytometry principles (>10 colors) and appropriate gating controls, panel design, optimization, and data analysis
• Hands-on experience in the analysis of human T cells and other immune cell types
• Experience with automated gating platforms for flow cytometry data analysis is required
• Demonstrated expertise with the use of commercial flow cytometry data analysis software such as FlowJo
• Ability to present complex data sets to key stakeholders and work effectively in a high paced team environment, meet deadlines, and prioritize work from multiple projects
• Familiarity with development and/or commercialization of cell-based therapeutics, including the development of analytical methods
• Familiarity with regulatory guidelines from the FDA, ICH, USP, etc.

What will separate you from the crowd

• Hands-on experience with advanced data visualization tools for single cell analysis such as SPADE, viSNE, and FlowSOM
• Knowledge of flow cytometry laboratory automation
• Experience working in a regulated GxP environment

What you should know

• Occasional weekend work
• Occasional travel between Sana locations
• Ability to work in BSL-2 and BSL-2+ labs
• Working safely on a predictable and regular basis is an essential job function for this position and the Company requires that all individuals, subject to certain exceptions, be fully vaccinated against COVID-19

How we work together

• Lead from every seat - we seek to understand, act with honesty, and engage in the crucial conversations
• Thrive as a team - we hire amazing people, are intensely curious, and cultivate inclusion and personal connectivity
• Make it happen - we value vigorous debate, alignment around our decisions, and resilient execution

Get to know us

At Sana, we believe that a diverse workforce strengthens us as a company and helps us to achieve our mission to meaningfully change the outcome of many human diseases. This belief is a pillar of our business and is critical to our success. Our goal is that Sana is the place for talented people to bring their authentic selves to work, to have a great career and to deeply, positively impact patients.

Core to our values, we believe there is nothing more important than the health and wellness of you and your family. We cover 100% of the cost for employee health coverage and offer generous time-off, parental leave, short- and long-term disability, financial wellness programs, a 401(k) Plan, Employee Stock Purchase Plan, commuter subsidy and a variety of wellness offerings to support each person individually.

We are committed to providing a workplace free of discrimination and harassment based on race, color, religion, age, gender, national origin, ancestry, physical or mental or sensory disability (including the use of a trained guide dog or service animal by a person with a disability), genetic information, actual or perceived HIV or Hepatitis C infection, medical condition (cancer or a record or history of cancer and genetic characteristics), marital status, sexual orientation, sexual preference, pregnancy (including childbirth and related medical conditions), disability, veteran status, political ideology, taking or requesting statutorily protected leave, status as a victim of domestic violence, sexual assault or stalking, or any other basis prohibited by applicable law.

To perform this job successfully, you must be able to perform each job responsibility satisfactorily. The job description listed above is representative of the knowledge, skills, and/or abilities required for this position. Reasonable accommodations may be made to enable individuals with disabilities to perform the functions described above.