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Research Associate, Assay Development (Multiple Openings)

Employer
Mammoth Biosciences
Location
Brisbane, CA
Start date
Sep 3, 2021

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Discipline
Regulatory, Research/Documentation, Science/R&D, Research
Required Education
Bachelors Degree
Position Type
Full time
Hotbed
Biotech Bay

Job Details

OPPORTUNITY
Mammoth is seeking a Research Associate, Assay Development experienced in protein and nucleic acid biochemistry techniques to support our research and product development teams. The ideal candidate will have experience in nucleic acid extraction, amplification and detection methods and techniques. The candidate will also have experience in handling a variety of human clinical sample types and experience with laboratory processes involving clinical samples. Furthermore, the candidate will be comfortable working as part of a team, be highly motivated, and display excellent time management skills.
KEY RESPONSIBILITIES
  • Contribute to CRISPR-based diagnostics assay optimization and reagent formulation development
  • Conduct experiments for sample processing, nucleic acid extraction, amplification, and related assays
  • Conduct clinical sample processing and testing on CRISPR-diagnostic assay in BSL 2+ laboratory
  • Participate in verification and validation studies
  • Perform data analysis of experiments and generate summaries for group meetings
  • Document information by maintaining lab notebooks and equipment record books
  • Resolve problems by examining and evaluating data and selecting corrective steps
  • Complete projects by assisting project team and attending and presenting in group and project meetings
  • Maintain quality compliance by participating in training and implementing approved quality procedures

REQUIRED QUALIFICATIONS
  • Bachelor’s in biology, chemistry or a related field
  • 2+ years industry experience in molecular biology and biochemistry
  • Experience processing different human sample types
  • Experience with designing and optimizing nucleic acid amplification (e.g. qPCR) and/or other molecular biology protocols

PREFERRED QUALIFICATIONS
  • Experience with in vitro CRISPR cis and trans cleavage assays 
  • Desire to work with infectious human samples
  • Ability to independently design, optimize and troubleshoot experiments
  • Exceptional skills in communication, presentation, data analysis, and interpretation
  • Highly motivated and detail-oriented with the ability to think creatively towards efficient problem solving

BENEFITS
  • Company-paid health/vision/dental benefits
  • Unlimited vacation and generous sick time
  • Company-sponsored meals and snacks
  • Wellness, caregiver and ergonomics benefits
  • 401(k) with company matching

Mammoth Biosciences, Inc. is harnessing the diversity of nature to power the next-generation of CRISPR products. Through the discovery and development of novel CRISPR systems, the company is enabling the full potential of its platform to read and write the code of life. By leveraging its internal research and development and exclusive licensing to patents related to Cas12, Cas13, Cas14 and CasPhi, Mammoth Biosciences can provide enhanced diagnostics and genome editing for life science research, healthcare, agriculture, biodefense and more. Mammoth is democratizing disease detection with easy and affordable point-of-care tests that allow real-time and simultaneous detection of multiple conditions, along with high-throughput tests that allow for unprecedented testing volume. Further, the company is transforming disease treatment with its proprietary micro-sized CRISPR proteins that enable new editing and delivery options. Based in Brisbane, CA, Mammoth Biosciences is co-founded by CRISPR pioneer and Nobel Prize winner Jennifer Doudna and principal founders Trevor Martin, Janice Chen, and Lucas Harrington. The firm is backed by top institutional investors including Decheng, Mayfield, NFX, and 8VC, and leading individual investors including Brook Byers, Tim Cook, Bob Nelsen, and Jeff Huber. 

TEAM
The Diagnostics team is advancing our CRISPR-based DETECTR™ platform to address unmet needs across the continuum of testing. From laboratories to the home, our mission is to democratize diagnostics with CRISPR. 

It is our policy and intent to provide equal opportunity to all persons without regard to race, color, religion, political affiliation, sex/gender (including gender expression/identity, pregnancy, childbirth and related medical conditions), marital status, registered domestic partner status, sexual orientation, age, ancestry, national origin, veteran status, disability, medical condition, genetic characteristics, and/or any other basis protected by law.  This policy covers all facets of employment including, but not limited to: recruitment, selection, placement, promotions, transfers, demotions, terminations, training, and compensation.

Company

Mammoth Biosciences is a biotechnology company focused on leveraging its proprietary ultracompact CRISPR systems to develop long-term curative therapies, as well as other applications such as decentralized precision diagnostics. Founded by CRISPR pioneer and Nobel laureate Jennifer Doudna and Trevor Martin, Janice Chen, and Lucas Harrington, the company’s ultracompact proteins are designed to enable in vivo gene editing in difficult to reach tissues utilizing both nuclease applications and new editing modalities beyond double stranded breaks, including base editing, gene writing, and epigenetic editing. The company is building out its pipeline of potential in vivo gene editing therapeutics and capabilities and has partnerships with leading pharmaceutical and biotechnology companies to broaden the reach of its innovative and proprietary technology. Mammoth’s deep science and industry experience, along with a robust and differentiated intellectual property portfolio, have enabled the company to further its mission to transform the lives of patients and deliver on the full promise of CRISPR technologies.

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Company info
Website
Phone
(650) 294-8583
Location
South San Francisco
CA
94080
United States

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