Associate Scientist, Protein Therapeutics

Associate Scientist, Protein Therapeutics
United States - California - Foster City

Gilead Sciences, Inc. is a research-based bio-pharmaceutical company that discovers, develops and commercializes innovative medicines in areas of unmet medical need. With each new discovery and investigational drug candidate, we seek to improve the care of patients living with life-threatening diseases around the world. Gilead’s therapeutic areas of focus include HIV/AIDS, liver diseases, cancer and inflammation, and serious respiratory and cardiovascular conditions.

Making an impact on a global scale
Inclusion is one of the company’s five core values. That’s because we know that we are stronger and more innovative at Gilead when we are informed by a diverse set of backgrounds, experiences and points of view. Gilead Sciences is a biopharmaceutical company that discovers, develops and commercializes innovative therapeutics in areas of unmet medical need. The company's mission is to advance the care of patients suffering from life-threatening diseases worldwide.

When you join Gilead, you join our mission to change the world by enabling people to live healthier and more fulfilling lives. Come join a mission-driven bio-pharmaceutical organization that values inclusion and diversity, has a strong portfolio of products, and is constantly #CreatingPossible


Gilead Sciences currently has an excellent opportunity for an associate scientist to join our protein chemistry group for small molecule drug discovery program. This person will work with a wide range of therapeutic areas in a highly productive environment. He or she will be responsible for generating recombinant proteins and collaborating with enzymology, high-throughput screening, and structural chemistry groups to support assay development, mechanism of action, and structural studies. The successful candidate should be self-driven, independent, and expected to work in a collaborative setting.

Functions and Responsibilities

• Independently design constructs and execute purification of protein targets across therapeutic areas using E coli, and Baculoviral expression systems
• Perform protein quality control experiments using techniques such as SDS-PAGE, Western blot, SEC-MAL, and HPLC
• Trouble shoot protein purification techniques using FPLC
• Encouraged to explore and innovate new techniques for protein sciences
• Participate in group and team meetings and present data
• Ability to interpret and draw conclusion from data and eager to work in a fast-paced environment
• Maintain knowledge of the advancement in the relevant scientific field
• Strong organization with respect to documentation of electronic notebook, report writing, and communication skills are essential

Education and Skills

• BS or MS in protein biochemistry, biology or related field
• 5-8 plus years of experience in protein purification and characterization
• Experience on structure-based design and engineering of protein targets
• Strong familiarity with the use of AKTA instruments and practical experience on protein purification techniques such as affinity, ion-exchange, and size-exclusion chromatography
• Knowledge on mass spectrometry and cell culture work is a plus
• Biotechnology/pharmaceutical industry experience is preferred
• Job title will be commensurate with experience

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