Skip to main content

This job has expired

You will need to login before you can apply for a job.

Scientist - Formulation Development

Employer
ReCode Therapeutics
Location
Menlo Park, CA
Start date
Aug 24, 2021

View more

Discipline
Science/R&D, Biotechnology
Required Education
Masters Degree/MBA
Position Type
Full time
Hotbed
Biotech Bay

Job Details

SCIENTIST - FORMULATION DEVELOPMENT

 

We are an integrated genetic medicines company developing targeted, disease-modifying medicines for patients with life-limiting respiratory diseases. Our treatments address the underlying genetic cause in underserved populations and have the potential to tremendously impact the quality and length of patients’ lives.

 

At ReCode, we bring a unique blend of rigor, creativity, and curiosity to our high-hurdle mission: harnessing our multi-platform approach to develop disease-modifying medicines. Our team is uniquely positioned to tackle this challenge, given our extensive experience in RNA delivery technologies, protein structure, tRNA biology, mRNA manufacturing, gene editing, and drug development.

 

THE ROLE

The incumbent will be responsible for development and optimization of formulation for lipid nanoparticle / RNA-based product candidates for preclinical and clinical development. In this role the candidate will work with cross-functional product development team including process development and analytical development to develop formulations with a good safety profile and high potency in vitro and in vivo.  

 

HERE’S SOME OF WHAT YOU’LL DO

  • Identify, prepare and analyze novel formulations to support product development.
  • Design experiments to conduct science-based formulation optimization.
  • Evaluate the effect of each formulation component on potency, safety, stability and aerosolization.
  • Summarize results, prepare development reports, and present data to product development team. 
  • Partner closely with colleagues conducting formulation evaluations, PK/PD, and in vitro and in vivo studies.
  • Provide formulations expertise and insights to various interdisciplinary teams.
  • Perform formulation transfer to process development teams and provide troubleshooting when needed
  •  

    HERE’S WHAT YOU’LL BRING TO THE TABLE

    • Minimally a Ph.D. in chemistry, bioengineering, chemical engineering, or a related discipline with at least one year of successful laboratory experience in lipid nanoparticles or other lipid-based drug delivery systems.  Comparatively, a candidate possessing an MS in chemistry, bioengineering, chemical engineering, or a related discipline with 6+ years of directly relevant experience will be considered. 
    • Strong foundation in chemistry, nanotechnologies for formulation design, nucleic acid therapeutics, and general pharmaceutical product research is required.
    • Understanding of the in-vitro and in-vivo experiments used for screening for candidate formulation required.
    • Experience with process development of complex mixtures a plus.
    • Strong written and oral communication skills.
    • Comfort in a dynamic and fast-paced scientific environment 

    ReCode Therapeutics (www.recodetx.com) offers a competitive compensation/benefits with a friendly, collaborative culture that values employee engagement and ongoing career development. ReCode Therapeutics is an Equal Opportunity Employer.


    Company

    The Why Behind Our Work

    We imagine a world where people living with genetic diseases can fully benefit from the promise of genetic medicines. Our novel mRNA and gene correction therapeutics have the potential to make this a reality.

    Therapeutic Areas of Focus

    Cystic fibrosis

    Primary ciliary dyskinesia

    Certain cancers and central nervous system (CNS) diseases

    Power the Next Wave of Genetic Medicine

    We are one of the rare companies whose innovations are poised to fundamentally shift an entire class of medicine.

    Join us as we advance our pipeline into clinical development and scale ReCode’s next-generation genetic medicines delivery platform and pipeline.

    Company info
    Website
    Phone
    408-585-1700
    Location
    1140 O'Brien Drive
    Menlo Park, CA 94025
    US

    Get job alerts

    Create a job alert and receive personalized job recommendations straight to your inbox.

    Create alert