Executive Director, Statistics
- Employer
- Pfizer
- Location
- Cambridge, MA
- Start date
- Jul 30, 2021
View more
- Discipline
- Science/R&D, Biostatistics, Research, Genetics
- Required Education
- Associate Degree
- Position Type
- Full time
- Hotbed
- Best Places to Work
The primary responsibility for the position is to establish and lead a world-class correlative sciences group, focusing on leveraging genomic, biomarker and related data to enhance and accelerate drug development across all therapeutic areas, including Oncology, Rare Diseases, Inflammation & Immunology and Internal Medicine. Specifically, the responsibilities include developing and implementing an enterprise-wide correlative sciences strategy, working closely with relevant stakeholders, including translational biology leads, precision medicine scientists, clinicians, study statisticians, computational biologists and statistical programmers.
The ideal candidate will:
- provide scientific leadership and technical support for Pfizer clinical projects involving biomarkers; lead the development and implementation of techniques based on state-of-the-art statistical research in correlative sciences; and seek creative solutions through collaborations and interactions with other experts for drug development problems.
- engage in methodological research and shape the external environment through scientific collaborations across academia, industry and regulators to advance drug development through effective use of biomarkers and related data.
- provide effective leadership to a group of biomarker statisticians and analysts at different levels, including senior directors.
- enhance expertise amongst Pfizer statisticians through dissemination of statistical knowledge, new methodologies and regulatory guidelines relating to correlative sciences.
- be recognized internally and externally as a thought leader in statistical aspects of correlative sciences.
- provide leadership in coordinating efforts across the enterprise to establish robust infrastructure to optimize biomarker and related data use.
Primary Duties:
- Provide leadership in the development and implementation of an enterprise-wide correlative sciences strategy, working closely with relevant stakeholders, including translational leads, precision medicine scientists, clinicians, study statisticians, computational biologists and statistical programmers.
- Ensure effective scientific leadership and technical support for Pfizer clinical projects involving biomarkers across all TAs, including Oncology, Rare Diseases, Inflammation & Immunology and Internal Medicine. Collaborate with product teams by the development and implementation of techniques based on state-of-the-art research. Provide statistical advice on complex statistical problems arising in Pfizer projects, especially those involving biomarker development and their application in clinical trials
- Develop effective collaborations with relevant non-statistical researchers (such as, Translational Biology, Clinical, Pharmacology, Development Operations, PharmSci, and Safety).
- Engage in methodological research and shape the external environment through scientific collaborations across academia, industry and regulators to advance drug development.
- Provide effective leadership to a group of statisticians at different levels, including senior directors.
- Increase expertise amongst Pfizer statisticians through dissemination of statistical knowledge, new methodologies and regulatory guidelines
- Lead the development and implementation of techniques based on state-of-the-art statistical research and seek creative solutions through collaborations and interactions with other experts for drug development problems.
- Exert external influence through collaborative partnership, scholarship and professional networking with academic, government and industry statisticians.
- Develop, implement, and promote methodologies based on state-of-the-art statistical research and dissemination of the results both internally and externally.
- Perform and assist with complex and novel study designs and data analyses and the development of specialized software to support them.
- Provide consultation on statistical issues to the Statistics Leadership Team, and Pfizer management in Translational Biology, Clinical Development, Medical Affairs, Regulatory and other pertinent groups.
- Participate actively in discussions towards inclusion of biomarker data in clinical trial designs,key go/no decisions, key regulatory and product defense strategies
- Provide a strong presence for Pfizer with regulatory and professional organizations to influence knowledge generation and content of regulatory guidelines and their interpretation in practice.
- Stay current with research on statistical methodology and its applications pertinent to the Pfizer business needs.
- Be up-to-date on training and compliance with all Pfizer SOPs as required based on the assigned curriculum.
- Ph.D. in Statistical Genetics, Statistics or Biostatistics.
- At least 15 years of experience in drug development involving biomarkers.
- Experience with implementation of a successful correlative sciences strategy, including at least 10 years of experience leading biomarker statisticians.
- Evidence of creative thought-leadership, professional presence, and scholarship through publications and presentations.
- Effective verbal and written communication skills in relating to colleagues and associates both inside and outside the organization.
- Broad-based understanding of statistical theory and its application.
- Candidate demonstrates a breadth of diverse leadership experiences and capabilities including: the ability to influence and collaborate with peers, develop and coach others, oversee and guide the work of other colleagues to achieve meaningful outcomes and create business impact.
PHYSICAL/MENTAL REQUIREMENTS
- Ability to perform complex data analysis, and other tasks specified in the job description.
- Relocation support available
- Directly reports to the Head of Statistical Research and Data Sciences (SRDC), within the Global Biometrics and Data Management organization
- Supervise a group of correlative science statisticians and analysts at different levels, including Senior Directors
Get job alerts
Create a job alert and receive personalized job recommendations straight to your inbox.
Create alert