Discovery Research Associate I/II/III/Sr.

Location
South San Francisco, CA, United States
Posted
Jul 26, 2021
Discipline
Science/R&D, Research
Hotbed
Biotech Bay
Required Education
Bachelors Degree
Position Type
Full time
Neurona Therapeutics is an early stage biotechnology company based in South San Francisco focused on the development of neuronal cell-based therapies for neurological disease. Our ideal candidate is a self-motivated individual who has a passion for scientific research. This is a fantastic opportunity to join a small team, work on transformative science, and take part in building an exciting, science-driven company. Research associate from level I to senior will be considered for joining our discovery team in order to develop methods for our next generation cell therapy products.

Responsibilities:
  • Maintain human pluripotent stem cells and perform differentiation into a variety of neuronal lineages (from 384 well plates to regular and large-scale culture vessels).
  • Develop cell-based screening assays using automated liquid handler for stem cell differentiation optimization.
  • Utilize High Content Screening (HCS) technology for high-throughput analysis of cell populations.
  • Characterize differentiated cells (immuno cyto-chemistry, Flow cytometry, RT-QPCR, RNA sequencing).
  • Conduct fluorescence or magnetic -activated cell sorting experiments.
  • Prepare tissue culture reagents (media, small molecules, cytokines); Tissue culture room upkeep and restocking.
  • Maintain detailed records.
  • Data analysis , compilation and presentation

Required Qualifications:
  • Bachelor's degree (+2 years of relevant experience) or Master degree in cell/molecular biology or related field.
  • Clear knowledge of sterile tissue culture technique (at least two years experience).
  • Familiar with pluripotent stem cell culture, in vitro directed differentiation paradigms and molecular/functional characterization of derived cell types.
  • Experience with automated liquid handlers to perform medium / high throughput cell-based screenings
  • Experience with coding (R, Python, ...) would be a plus.
  • Willing to work a limited number of hours during weekends.
  • Excellent writing, verbal communication, and interpersonal skills, proficiency with Microsoft office.
  • Able to take initiative to improve work processes, develop innovative scientific methodologies and approaches to enhance research productivity.
  • High integrity, great organization proactive and ability to multitask while working within fast-paced timelines
  • Strong team player and problem-solver

Preferred Qualifications:
  • At least one year of solid experience with human pluripotent (embryonic or induced) stem cell maintenance, differentiation, cell sorting and immuno cyto chemistry.
  • One year of experience with lab automation for cell-based screening assays using liquid handling automates (protocol creation, hands on automates)
  • Experience with transcript- and protein-based gene expression analyses, high content screening.
  • Knowledge of human developmental biology.


Interested in learning more about our science and our team? Please visit our website at www.neuronatherapeutics.com.

Neurona is proud to be an equal opportunity employer and will consider all qualified applicants for employment.