Amgen

Postdoctoral Fellow - Cardiometabolic Disorders

Employer
Amgen
Location
South San Francisco, CA
Posted
Jul 24, 2021
Ref
R-124024
Required Education
Doctorate/PHD/MD
Position Type
Full time

HOW MIGHT YOU DEFY IMAGINATION?

Do more with the knowledge youre working hard to acquire and the passion you already have. At Amgen, our shared missionto serve patientsdrives all that we do. It is key to our becoming one of the worlds leading biotechnology companies, reaching over 10 million patients worldwide. Through this program, you will acquire the valuable hands-on skills and foundational experience to become the professional you are meant to be in your chosen field.

Postdoctoral Fellow Cardio-metabolic Research

Live

This could be your everyday

Lets do this. Lets change the world. During this program, you will be provided with an enriching environment to inspire innovation that will contribute to the development of human therapeutics.

The lab of Dr. Jixin Cui and Dr. Saptarsi Haldar in the Cardiometabolic Disorders Research Department at Amgen is seeking a highly motivated postdoctoral fellow to perform independent research to understand how the protein quality control machinery regulates cardiomyocyte function during heart failure.

The postdoctoral fellow will leverage human genetic evidence and take a multi-disciplinary approach combining cell biology, biochemistry, proteomics, structural biology, and animal models to identify novel mechanisms by which genetic variants in chaperones and co-chaperones alter the risk for cardiomyopathy and heart failure. The successful candidate will have the opportunity to make key scientific contributions to and establish him/herself in the field of protein homeostasis in human heart failure. He/she will be encouraged and expected to independently develop a research program based on initial studies and to present at scientific conferences and publish in leading journals. The postdoctoral fellow will enjoy strong support in using Amgens cutting-edge technologies and interact closely with a cross-functional team of Amgens distinguished scientists.

The postdoctoral position is for 3 years with the option to extend for an additional year.

Win

Heres what it takes to Win

We are all different, yet we all use our unique contributions to serve patients. The dedicated individual we seek is a scientist with these qualifications.

Basic qualifications

  • PhD at the time of appointment

Preferred qualifications

  • PhD in cell biology, biochemistry, molecular biology, or physiology
  • Previous research experience in one of the following areas: protein quality control, heat shock proteins, cardiovascular biology, cardiomyocyte function
  • Expertise in one of the following techniques: human induced pluripotent stem cell-derived cardiomyocytes (hiPSC-CMs), functional characterization of cardiomyocytes, animal models of heart failure, isolation and culture of primary cells, protein engineering
  • Record of independent critical thinking and the ability to design, execute, and interpret experiments, as exemplified by high-quality publications

Our culture is what makes Amgen a special place to work. We have a powerful shared purpose around our mission to serve patients. We respect one another, recognize contributions, and have embedded collaboration, trust, empowerment, and inclusion in all that we do.

Thrive

Some of the vast rewards of working here

As we work to develop treatments that take care of others, so we work to care for our teammates professional and personal growth and well-being.

  • Full support and career-development resources to expand your skills, enhance your expertise, and maximize your potential along your career journey
  • A diverse and inclusive community of belonging, where teammates are empowered to bring ideas to the table and act
  • Generous Total Rewards Plancomprising health, finance and wealth, work/life balance, and career benefitswith compensation and benefits rated above 4 stars (out of 5) on Glassdoor

Equal Opportunity Statement

Amgen is an Equal Opportunity employer and will consider you without regard to your race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, or disability status.

We will ensure that individuals with disabilities are provided a reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. Please contact us to request an accommodation.


Join Us

If you're seeking a career where you can truly make a difference in the lives of others, a career where you can work at the absolute forefront of biotechnology with the top minds in the field, you'll find it at Amgen.

Amgen, a biotechnology pioneer, discovers, develops and delivers innovative human therapeutics. Our medicines have helped millions of patients in the fight against cancer, kidney disease, rheumatoid arthritis and other serious illnesses.

As an organization dedicated to improving the quality of life for people around the world, Amgen fosters an inclusive environment of diverse, ethical, committed and highly accomplished people who respect each other but compete intensely to win. Together, we live the Amgen values as we continue advancing science to serve patients.

Amgen is an Equal Opportunity employer and will consider all qualified applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, or disability status.

Amgen will consider for employment qualified applicants with criminal histories in a manner consistent with the San Francisco Fair Chance Ordinance.