Scientist, Non-Viral Vector Analytical Development

Cambridge, MA, United States
Jul 22, 2021
Required Education
Position Type
Full time
Why Join Intellia?

Our mission is to develop curative genome editing treatments that can positively transform the lives of people living with severe and life-threatening diseases.

Beyond our science, we live our four core values: One, Explore, Disrupt, Deliver and feel strongly that you can achieve more at Intellia. We have a single-minded determination to excel and succeed together. We believe in the power of curiosity and pushing boundaries. We welcome challenging thoughts and imagination to develop innovative solutions. And we know that patients are counting on us to make the promise a reality, so we must maintain high standards and get it done.

We want all of our people to go beyond what is possible. We aren't constrained by typical end rails, and we aren't out to just treat people. We're all in this for something more. We're driven to cure and motivated for change. Just imagine the possibilities of what we can do together.

How you will Achieve More with Intellia

As a Scientist in the Non-Viral Vector Biology group, you will help advance Intellia's gene-editing platform and pipeline. In this role, you will work collaboratively with our research group, process development group, and our internal manufacturing team to identify, develop, and implement appropriate analytical methods for characterizing synthetically produced DNA payloads.

Key responsibilities include:
  • Development and qualification of analytical methods for the release and characterization of synthetic DNA products, in-process controls, and starting materials
  • Design, plan, and execute experiments in analytical development, working both independently and as part of a multidisciplinary team of researchers, including partnering closely with the process development team
  • Introduce new analytical technologies and implement common reagents and controls
  • Tech transfer research-scale processes to Intellia's internal manufacturing team
  • Author and review SOPs and method qualification protocols
  • Interpret and communicate data as part of multi-disciplinary teams
  • Maintain a detailed electronic laboratory notebook

About You

We are seeking an innovative Scientist with expertise in analyzing and qualifying nucleic acid drug products. The ideal candidate thrives on working collaboratively with multidisciplinary teams, displays outstanding communication skills, and is passionate about pioneering new gene-editing technologies to treat diseases. Other important qualities include:
  • Ph.D. in Chemistry, Chemical Engineering, Biomolecular Engineering, Biochemistry, or a related field
  • Hands-on experience optimizing and executing nucleic acid testing and characterization techniques (e.g. HPLC, SDS-PAGE, CD, DLS, SEC-MALS, AF4-MALS, ELISA, NGS, cell-based potency assays)
  • General knowledge of non-viral delivery methods, LNP formulation, and standard molecular biology laboratory techniques
  • Excellent bench skills with attention to detail and high standards for data integrity and quality
  • Highly organized
  • Strong communication skills with the proven ability to work collaboratively
  • Passion for applying new techniques and technologies

Meet your Future Team

The Platform Innovation team is a collaborative, energetic, and passionate group of individuals whose mission is to advance and differentiate Intellia's platform to enable curative therapies. You will join a team with vector design and production expertise, and work closely with leaders in the field of CRISPR/Cas9 gene editing. The candidate will have many opportunities to broaden his or her experience with multiple cutting-edge gene therapy technologies that advance Intellia's pipeline.

The team is currently working mostly onsite to execute workflows in a wet-lab environment. Therefore, the candidate must be local to Cambridge MA, or open to relocating. While some of the day-to-day operations may be home-office-based, maintaining a strong relationship with your teammates is critical for conveying your scientific expertise while fostering an environment for the growth of young scientists interested in a career in the biotech industry. If you join us, you can expect to be part of a hardworking and collaborative environment. We look forward to fostering your skills, learning from your experiences, and building a larger team to make a difference in patients' lives.


EEOC Statement: Intellia believes in a diverse environment, and is committed to equal employment opportunity for all its employees and qualified applicants. We do not discriminate in recruitment, hiring, training, promotion or any other employment practices for reasons of race, color, religion, gender, national origin, age, sexual orientation, marital or veteran status, disability, or any other legally protected status. Intellia will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law.