R&D Specialist, Formulation Development

Location
Working from home
Posted
Jul 19, 2021
Ref
24713BR
Required Education
Bachelors Degree
Position Type
Full time
We are seeking a R&D Specialist within the Formulation Development Group of Regeneron Pharmaceutical Inc. at Tarrytown, NY. The R&D Specialist will be involved with clinical and commercial formulation and drug product development activities including protein stability and characterization. The Specialist will also support manufacturing process development, gene therapy modalities, and drug delivery technologies.

A Typical Day in the Role of Specialist Might Look Like:
• Designs and executes formulation and stability studies to support various phase-appropriate drug development of antibodies and other modalities (e.g. siRNA).
• Develops and performs characterization of candidate molecules using various biophysical and biochemical techniques to identify critical quality attributes.
• Characterizes the drug product (lyophilized or liquid) formulation to support manufacturing of clinical drug substances and drug products.
• Develops fit-for-purpose analytical methods to support biophysical characterization, formulation and process development and research stability testing.
• Collect, process and document data by following organizational policies.
• Utilizes statistical knowledge and software packages (e.g. JMP) for study design and data analysis.
• Participates in meetings and communicates results in team meetings or department meetings.
• Authors technical documents for internal use and supports regulatory filings.

This Role Might Be For You If:
• You have an excellent problem-solving approach
• You thrive in a creative, flexible team environment

B.S. with 5+ years or M.S. with 2+ years experience in Pharmaceutical Sciences, Biochemistry, Biophysics, Chemistry, Biomedical Engineering, Chemical Engineering, or a related field. Relevant proven experience preferred. Strong technical knowledge base and meaningful experience with protein/peptide chemistry, biophysical/biochemical characterization of proteins, bioanalytical method development and biomolecule product development is desirable. Experience with chromatography methods (HPLC, UPLC, column chromatography,CEX, AEX, SEC, IPRP, RP), visible and subvisible particle analysis (MFI, HIAC), capillary electrophoresis (MCE, iCIEF) and/or biophysical techniques (UV-vis, DLS, FTIR, DSC, AUC, Fluorescence, Raman spectroscopy) for characterization is desirable. Knowledge of gene therapy modalities (siRNA, LNP, AAV, etc.) is a plus.

Does this sound like you? Apply now to take your first steps toward living the Regeneron Way! We have an inclusive and diverse culture that provides amazing benefits including health and wellness programs, fitness centers and stock for employees at all levels!

Regeneron is an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion or belief (or lack thereof), sex, nationality, national or ethnic origin, civil status, age, citizenship status, membership of the Traveler community, sexual orientation, disability, genetic information, familial status, marital or registered civil partnership status, pregnancy or maternity status, gender identity, gender reassignment, military or veteran status, or any other protected characteristic in accordance with applicable laws and regulations. We will ensure that individuals with disabilities are provided reasonable accommodations to participate in the job application process. Please contact us to discuss any accommodations you think you may need.