Associate Scientist, Analytical Development (cell based, functional, flow assays)

Philadelphia, PA, United States
Jul 17, 2021
Pharm Country
Required Education
Bachelors Degree
Position Type
Full time
Company Background:

Century Therapeutics is developing novel allogeneic living cell products for oncology that overcome the limitations of current cell therapies. Century's genetically-engineered, universal iPSC-derived immune effector cell products are designed to specifically target hematologic and solid tumor cancers. Our commitment to developing off-the-shelf cell therapies will expand patient access and provide an unparalleled opportunity to advance the course of cancer care.

Century's foundational technology is built on induced pluripotent stem cells (iPSCs) that have unlimited self-renewing capacity. This enables complex cellular engineering to produce controlled cell banks of modified cells that can be expanded and differentiated into desired immune effector cells, which can supply vast amounts of allogeneic, homogeneous therapeutic products. This platform differentiates Century from other approaches that utilize non-renewable donor-derived cells.


The Associate Scientist, Analytical Development is responsible for developing, optimizing, validating, and transferring analytical methods for the release and characterization of Century's genetically-engineered cell therapy products. in support of early development programs. This role will interact extensively with internal and external partners to advance pipeline programs through key CMC milestones. The successful candidate will need strong scientific background, interpersonal skills, and ability to work collaboratively with other groups across organizations.

This role is based in Philadelphia (University City), PA.

  • Assist in developing, executing, and documenting analytical methods in support of release and characterization of genetically-engineered cell therapy products, with a focus on cell-based, flow cytometry, and ELISA assays
  • Maintain, calibrate, and operate analytical equipment
  • Author technical and scientific documents including protocols, reports, and SOPs
  • Support tech transfer of methods to manufacturing for internal and external QC testing
  • Participate in assay validation activities
  • Support preparation of CMC documents for regulatory filings
  • Foster a collaborative and scientifically rigorous team culture

  • B.S. or M.S. in Biochemistry, Cell Biology, Molecular Biology, Biotechnology, Biological Sciences or related discipline
  • At least 4 years (with B.S.) or 2-4 years (with M.S.) of relevant professional experience

  • Experience with cell-based, flow cytometry, and ELISA assays
  • Knowledge of cell culture
  • Excellent oral and written communication skills

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