Research Associate / Senior Research Associate
The successful candidate will be part of an in vivo pharmacology team focusing on the validation and advancement of novel cancer therapeutic candidates. The candidate will perform hands-on experiments on rodents to examine the efficacy and mechanism of action of our anticancer therapeutics.
Major Responsibilities and Duties:
Perform in vivo studies to test oncology and immune-oncology therapeutics. Hands-on work will include cell culture, generating xenograft tumor models, intravenous (IV), intraperitoneal (IP), and intragastric (PO) dosing of mice, as well as isolation of mouse blood (via various routes) and tissues. Support ex vivo analysis to examine drug pharmacodynamics and biomarker discovery. Analyze and present data as well as rationale and design of in vivo studies to the department and project teams. Work collaboratively on multiple projects concurrently and coordinate activities across functions.
1) Bachelor's or Master's degree in Biology/Oncology.
2) At least 1-5 years of hands-on in vivo experience with mice, including generating and measuring xenograft tumors, dosing via intravenous, intraperitoneal, and intragastric administration, and collection of mouse tissue and blood is required.
3) Basic cell culture experience is required.
4) Hands-on experience with various in vitro laboratory techniques will be a plus, including Western blot, qRT-PCR, ELISA, immunohistochemistry, and flow cytometry.
5) Capable of working independently in a fast-paced, team-oriented environment, demonstrating multitasking capabilities.
6) Excellent troubleshooting and data analysis skills are required.
7) Great communication skills and team spirit is a must; ability to communicate results within pharmacology team and at project team meetings required.
8) Previous industry experience is a plus.