Research Scientists in genetically engineered T cells

Location
Rockville, MD
Salary
Salary is commensurate with experience.
Posted
Jul 15, 2021
Required Education
Bachelors Degree
Position Type
Full time

Research Associate, Senior Research Associate, or Research Scientist

Neomics Pharmaceuticals is a venture-backed pre-clinical immunotherapy company focused on the development of novel immunotherapies targeting solid and hematopoietic tumors aimed at transforming the lives of people diagnosed and living with cancer. Our research is focused on advancing our lead compounds through pre-clinical development and into Phase I/II trials while broadening our pipeline to include new therapeutic targets and multicomponent engineering to improve the efficacy of the therapeutic product. We are headquartered in Rockville, Maryland.

We are currently seeking a Senior Research Associate or Research Scientist to join our research team. Reporting to a senior scientist you will work on the development and testing of our next-generation CAR-T cell therapeutic pipeline. You will be responsible for the production of genetically engineered T cells, cell culture, and in-vitro analysis of the T cell product, and will participate in the design, execution, and interpretation of in-vivo animal models in coordination with local CROs. You will participate in the development of new technologies, and support technology transfer, licensing, and patent-preparation efforts. At times, you will oversee the efforts of a research associate and the position offers excellent opportunities for career development in a highly collaborative setting.

Education and Experience

The position is offered at a Research Associate, Senior Research Associate, or Research Scientist level, based on candidate education and experience. The successful candidate will have an in-depth understanding of T cell biology or Cancer Immunotherapy with specific experience in the generation and testing of Chimeric Antigen Receptors greatly preferred.

  • Research Associate
  • Bachelors in immunology or cellular biology or a closely related field, with 0-1 years of experience.
  • Senior Research Associate
  • Masters in immunology, cellular and/or tumor biology or a closely related field, or a bachelor’s with 2-3 years of experience working in either industry or an academic research setting.
  • Research Scientist
  • Ph.D. in immunology, cellular and/or tumor biology or a closely related field with a publication list that demonstrates your productivity and capacity.

Desirable Skills for Senior Research Associate or Research Scientist Position

  • The candidate should have a strong background in cancer immunotherapy or human immunology and experience working with engineered T-cells appropriate for the position
  • Hands on experience in the development, testing, and analysis of Chimeric Antigen Receptor (CAR)-T or T Cell Receptor (TCR)-T cells is highly preferred.
  • Proficient in molecular biology and cellular biology techniques, including PCR, qRT-PCR, cloning, and western blot.
  • Highly proficient in flow cytometry and cell sorting techniques as well as flow-based immunophenotyping. This should include panel design, sample acquisition and data processing). Experience with human T cells is highly preferred.
  • Experience designing, executing, and analyzing immune cell assays (in-vitro cytotoxicity, cytokine production, proliferation, and phenotyping) to evaluate CAR/TCR functionality.
  • Hands on experience in the isolation, culture and genetic modification (viral and non-viral) of human T cells
  • Proficient in aseptic cell culture
  • Ability to reach rational conclusions based on available data and competent analysis.
  • Able to work with minimal direction and oversight, adjusting workload and priorities as needed.

Desirable Characteristics

The candidate should be driven by accomplishments and excellence in the workplace, executing on the company’s mission and values while maintaining a high degree of ethical standards and trustworthiness. The preferred candidate should be able to execute their daily duties with a high degree of accuracy and attention to detail in both independent work and in team projects. The ideal candidate should be able to drive their own projects through innovation and creative solutions while contributing ideas and expertise to others in order to successfully drive the success of the company in a team environment.