Senior Research Associate - Assay Development

Menlo Park, CA, United States
Jul 14, 2021
Biotech Bay
Required Education
Bachelors Degree
Position Type
Full time
GRAIL is a healthcare company whose mission is to detect cancer early, when it can be cured. GRAIL is focused on alleviating the global burden of cancer by developing pioneering technology to detect and identify multiple deadly cancer types early. The company is using the power of next-generation sequencing, population-scale clinical studies, and state-of-the-art computer science and data science to enhance the scientific understanding of cancer biology, and to develop its multi-cancer early detection blood test. GRAIL is headquartered in Menlo Park, CA with locations in Washington, D.C., North Carolina, and the United Kingdom. It is supported by leading global investors and pharmaceutical, technology, and healthcare companies. For more information, please visit

GRAIL is seeking a Senior Research Associate in the Assay Development team at our headquarters in Menlo Park to perform studies to support the development and integration of GRAIL's groundbreaking cancer screening products. You will contribute to wet-lab research and development studies in support of IVD product development goals, including the planning and execution of experiments and data analysis under the guidance of senior scientists. The ideal candidate is a detail-oriented positive teammate with experience in automated NGS assay development and IVD products.

You Will:

• Plan, execute, and perform analysis of R&D experiments in collaboration with senior scientists
• Execute integration and development studies to generate high quality data by following best practices of assay and instrument operations
• Test and optimize custom protocols
• Support implementation and operations teams in troubleshooting activities
• Ensure laboratory activities are performed in compliance with safety guidelines and best practices
• Document experimental details in electronic form and support writing of protocols and reports
• Perform preliminary data analysis and support presentation and documentation of experimental results
• Ensure technical activities are in line with regulatory requirements (CAP/CLIA/FDA)

Your Background Will Include:

• B.S. or M.S. degree in Molecular Biology, Biochemistry, or relevant fields with a minimum of 3 years of work experience in an industry setting
• Hands-on experience with Illumina NGS workflow including DNA extraction, library preparation, target enrichment, and sequencing
• Hands-on experience with automated laboratory instrumentation such as liquid handlers and multi-functional workcells a plus
• Experienced with standard nucleic acid analytical techniques (e.g, qPCR, Nanodrop, Fragment Analyzer, ddPCR)
• Experience with statistical programming or software (e.g, R, JMP) a plus
• Experience with the development, optimization, and troubleshooting of NGS assay protocols a plus, in particular on automated systems
• Experience with the development and implementation of clinical laboratory tests under CAP/CLIA or FDA/regulated environments
• Experience with design control and change control.
• Attention to detail, safety, good laboratory practice, and good documentation practice
• Strong verbal and written communication skills and willingness to collaborate cross-functionally in a fast-paced and dynamic environment

We are an equal opportunity employer and value diversity at our company. We do not discriminate on the basis of race, religion, color, national origin, gender, sexual orientation, age, marital status, veteran status, or disability status.

GRAIL, Inc. and its affiliates and subsidiaries ("GRAIL") does not accept any liability for fees for resumes from recruiters or employment agencies ("Agency"), without a binding, written recruitment agreement between GRAIL and Agency describing the services and specific job openings ("Agreement"). GRAIL may consider any candidate for whom an Agency has submitted an unsolicited resume and explicitly reserves the right to hire those candidate(s) without any financial obligation to the Agency, unless an Agreement is in place. Any email or verbal contacts with any person within GRAIL is inadequate to create a binding agreement. Agencies without an Agreement are requested not to contact any hiring managers of GRAIL with recruiting inquiries or resumes. Agencies interested in partnering with GRAIL may contact GRAIL's HR Department through our Customer Service team .