Senior Associate Scientist, Platform Innovation, Histology

Why Join Intellia?

Our mission is to develop curative genome editing treatments that can positively transform the lives of people living with severe and life-threatening diseases.

Beyond our science, we live our four core values: One, Explore, Disrupt, Deliver and feel strongly that you can achieve more at Intellia. We have a single-minded determination to excel and succeed together. We believe in the power of curiosity and pushing boundaries. We welcome challenging thoughts and imagination to develop innovative solutions. And we know that patients are counting on us to make the promise a reality, so we must maintain high standards and get it done.

We want all of our people to go beyond what is possible. We aren't constrained by typical end rails, and we aren't out to just treat people. We're all in this for something more. We're driven to cure and motivated for change. Just imagine the possibilities of what we can do together.

How you will Achieve More with Intellia:

We are excited to welcome the Associate Scientist to our growing team and company. In this role, you will help support the characterization and quantitation of LNP delivery and gene editing events using immunohistochemistry and in situ hybridization. You will work on various key projects including:

• Design, implement, and troubleshoot experiments, both independently and in collaboration with colleagues, to reach desired goals
• Develop and perform immunohistochemistry assay (both chromogenic or fluorescent) on FFPE or cryosection slides
• Perform RNAscope/Basescope in situ hybridization assay
• Conduct image analysis using software such as HALO, QuPath and imageJ
• Accurately document project and sample information, protocols, and experimental details documentation through Electronic Lab Notebook (ELN) to drive decision making across different internal teams

About You:

This is a primarily hands-on role. If you are a strong and independent problem-solver, agile, detail-oriented with a strong technical background in histology, and enjoy working in cross-functional teams, this is the role for you! Additional requirements include:

• B.S. in biology or related field with 7 -10 years of academic or industry experience
• Hands-on experience in all aspects of histology, especially IHC and/or ISH
• Experience in the histology/pathology core labs
• Familiarity with digital slide scanner and fluorescent microscopy
• Familiarity with image analysis software (HALO, QuPath, imageJ or other similar software)

Meet your future team:

The Platform innovation team is a group of bright, fun, and team-first individuals. Eager to move cool projects forward, we are motivated at the opportunity to make an impact on patients. The breadth of exposure to cutting-edge gene therapy development will provide you with exposure to the full spectrum of gene and cell-based therapies, starting from CRISPR guides to patients who we try our best to support. You will report to a Principal Scientist, Imaging , who is involved in many of Intellia's high priority projects in LNP delivery and disease biology.

The team is currently working mostly onsite in a wet-lab environment, therefore, you will need to either be local to our Cambridge, MA office or open to relocating. While much of the day-to-day operations require wet-lab work, our team is focused on building not just technical expertise but fostering an environment for the growth of scientists interested in a career in therapeutic biotechnology. If you join our team, you can expect to join a fast, fun, exciting and collaborative environment. We look forward to fostering your skills, learning from your experiences, and building a larger team together.

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EEOC Statement: Intellia believes in a diverse environment, and is committed to equal employment opportunity for all its employees and qualified applicants. We do not discriminate in recruitment, hiring, training, promotion or any other employment practices for reasons of race, color, religion, gender, national origin, age, sexual orientation, marital or veteran status, disability, or any other legally protected status. Intellia will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law.