Senior Research Associate, In Vivo Pharmacology

Overview

Imagine\u2026 2 weeks after the birth of your child you realize they aren't meeting critical developmental milestones and after months of doctor's appointments you are told your baby has a rare neurological disease that would impact how they would live their lives. This is the reality of parents whose children have Spinal Muscular Atrophy (SMA) and it's the reason why we at Novartis Gene Therapies are laser focused on bringing hope and possibility to those devastated by rare genetic diseases.

The Senior Research Associate, In Vivo Pharmacology , is responsible for animal care and handling including breeding, dosing, executing in vivo experiments and tissue collection under supervision of scientists in support of pipeline development.

Responsibilities

• Perform high level tasks and play a lead role in animal care and handling including breeding, dosing, executing in vivo experiments under limited supervision of scientists, and tissue collection related to existing and pipeline products.
• Performs high-level tasks necessary for the husbandry and study of rodent models of disease such as animal identification by marking, breeding, weaning, and collection of tissue samples for DNA or RNA analysis. Plays a lead role and oversees day to day activities of other Research Associates.
• Establish protocols for behavioral studies and execute behavioral testing.
• Partner with lead scientists in research and development to validate, characterize, and distribute mouse models that directly address drug discovery and program validation.
• Work interactively with research and development team to validate, characterize, and distribute mouse models that directly address drug discovery and program validation.
• Executes, tracks, and manages genotyping.
• Leads research associates to organize, schedule and execute experimental work.
• Examine data and prepare technical reports, summaries, protocols and quantitative analysis, ensuring experiments are well documented and comply with regulatory requirements. Field questions from research associates and escalate to scientific leadership as necessary. Assist in troubleshooting.
• Maintain and ensure safe laboratory environment and work practices. Follow standard operating procedures (SOP) and IACUC protocols. Help to maintain laboratory.
• Work collaboratively across a dynamic scientific environment.
• Other related duties as assigned.

Qualifications

• Bachelor's degree in biomedical research, neuroscience, animal behavior or animal sciences with 4 years related experience or 7 years of equivalent education/experience may be accepted.
• 5 years experience in rodent handling.
• Excellent oral and written communication skills.
• Proficiency with standard in vivo techniques in rodents, including dosing and sampling routes (e.g., po, ip, sc, iv dosing; cardiac bleeds; necropsy and organ/tumor harvest).
• Preferred - Experience with transcardiac perfusion.
• Preferred - Experience characterizing rodent models of various human diseases with behavioral testing.
• Preferred - Previous industry experience.

The level of this position will be based on the final candidate's qualifications.

Why Novartis?

769 million lives were touched by Novartis medicines in 2020, and while we're proud of this, we know there is so much more we could do to help improve and extend people's lives. We believe new insights, perspectives and ground-breaking solutions can be found at the intersection of medical science and digital innovation. That a diverse, equitable and inclusive environment inspires new ways of working.

We believe our potential can thrive and grow in an unbossed culture underpinned by integrity, curiosity and flexibility. And we can reinvent what's possible, when we collaborate with courage to aggressively and ambitiously tackle the world's toughest medical challenges. Because the greatest risk in life, is the risk of never trying! Imagine what you could do here at Novartis!

Novartis Gene Therapies Benefit Summary:

Annual bonus, long term incentive, health insurance, paid vacation/holidays, potential flexible working arrangements (based on role) and an employee recognition program are available for this position, among many other benefits provided to employees of Novartis Gene Therapies.

Please note this job description is not designed to cover or contain a comprehensive listing of activities, duties or responsibilities that are required of the employee for this job. Duties, responsibilities and activities may change at any time with or without notice.

Novartis Gene Therapies is committed to creating a diverse environment and is proud to be an equal opportunity employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, gender, gender identity, national origin, genetics, disability, age, sexual orientation or veteran status.

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