Senior Computational Biologist / Computational Biologist
- Employer
- Maze Therapeutics
- Location
- South San Francisco, CA, United States
- Start date
- Jul 12, 2021
View more
- Discipline
- Science/R&D, Biology
- Required Education
- Bachelors Degree
- Position Type
- Full time
- Hotbed
- Biotech Bay
Job Details
We are seeking a talented and highly motivated scientist to help build and expand our computational biology discovery platform. The successful candidate will join a team of data scientists, computational biologists, bench scientists, and automation engineers to mobilize genetics and functional genomics data towards the discovery of new therapeutic targets and drugs.
Your Role in Navigating The Maze:
- You will become an integral member of our target and drug discovery teams, helping to move programs from concept to the clinic
- You will help design and interpret functional genomics and computational biology experiments, often integrating data from genetics and external sources
- You will work with the Human Genetics, Functional Genomics, Stem Cell and Drug Discovery departments to design and implement cutting-edge analysis and visualization tools and production-quality bioinformatics pipelines
- You will communicate data and scientific results to both internal and external audiences, advise on analytical and statistical best practices, and contribute to open-source and collaborative projects
- You will propose new approaches and methods using your computational biology expertise, elevating our ability to break barriers in target discovery
Your Navigation Tools:
- Advanced degree (or equivalent experience) in computational biology, bioinformatics, statistics, or other scientific field that has relevance to high-dimensional biological data; 2+ years' experience (industry or academic) is preferred
- Demonstrated success developing and applying statistical and computational methods for analyzing and interpreting diverse functional genomics experiments
- Familiarity with pipelines and best practices for analyzing genomics data and diverse modern applications of sequencing technologies (including various high throughput and single cell applications)
- Extensive experience in the use of a high-level programming language (particularly R/Bioconductor, or Python/Pandas)
- A demonstrated ability to understand scientific needs from multiple R&D functions and a drive to bring complex projects to successful conclusion
- Experience working and communicating with diverse scientific teams; strong data presentation, analytical and visualization skills
- A highly motivated, proactive and “can-do” disposition
Company
Maze Therapeutics is translating novel genetic insights into lifesaving medicines, through an approach that integrates human genetics and functional genomics. Advances in these areas have enabled us to decode the mysteries of genetic modifiers in a range of severe diseases, which we aim to turn into medicines that mimic protective mutations.
What are genetic modifiers?
Despite an understanding of the genetic basis for many diseases, it remains a mystery why some people with a disease-causing mutation never get sick. This is often due to genes elsewhere in our DNA that affect the severity of disease and can provide a natural form of protection.
The Maze approach
Dramatic advances in human genetics and functional genomics now enable us to decode the mysteries of genetic modifiers in a range of severe diseases. Today, we believe we can systematically identify genetic modifiers and turn these insights into medicines. We have assembled a world-class team to realize this vision, including creative scientific pioneers, experienced company builders and biotech industry leaders.
Join us in our pursuit to change lives by translating genetic insights into medicine - view our job postings with the link to the left.
- Website
- https://mazetx.com/
- Location
-
171 Oyster Point Blvd, Suite 200
South San Francisco
CA
94080
United States
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