Research Associate III (In Vivo/Oncology)
- Employer
- Nektar Therapeutics
- Location
- San Francisco, CA, United States
- Start date
- Jul 12, 2021
View more
- Discipline
- Science/R&D, Research, Oncology
- Required Education
- Bachelors Degree
- Position Type
- Full time
- Hotbed
- Biotech Bay
Job Details
Nektar has an exciting opportunity for a Research Associate III (In Vivo/Oncology) to join their Research Biology Pharmacology Team.
We are seeking a highly motivated individual who is highly proficient in vivo tumor models establishment and execution and in vivo drug administration by multiple routes, disease scoring and tissue sample collection for ex vivo assays.
Responsibilities:
- Conduct in vivo pharmacological evaluation of test agents (small molecules and biologics) in syngeneic and xenograft tumor models.
- Proven skills in cell culture and tumor inoculation with cell lines
- Conduct in vivo oncology models, administering test articles (i.v., s.c., i.p., i.d. and p.o.), making in vivo tumor measurements, collecting samples for ex vivo assays. May assist in sample processing, homogenization, and generation of single-cell suspensions for ex vivo analysis including flow cytometry, blood and plasma cytokine measurements.
- Candidate will be responsible for entering and assist in analysis of data from concurrent multiple tumor studies in a timely manner and must be able to communicate experimental results orally and assist in reports and regulatory documentation writing.
- Maintain familiarity with current disease relevant in vivo models for testing of mechanism of action and efficacy of novel drug candidates to support preclinical development and investigational new drug application filings.
- Contribute to development of new xenograft and syngeneic liquid and solid tumor models (murine).
- Exercises technical discretion in interpreting study designs, execution and interpretation of experiments that contribute to project strategies.
- Performs research and/or development of new protocols independently and in collaboration with others in a highly integrated collaborative team environment with strong sense of individual responsibility.
- Maintains a high level of professional expertise through familiarity with scientific literature.
- Ensures compliance with good laboratory practices, AAALAC, IACUC, and other regulatory guidelines.
A minimum of a Bachelor's degree in a scientific discipline is required. Equivalent experience may be accepted. A minimum of 5 years work experience in a research and/or development environment is required.
Additional Requirements Include:
- Highly skilled in conducting in vivo oncology models, administering test articles (i.v., s.c., i.p., i.d. and p.o. required), making in vivo tumor measurements, collecting samples for ex vivo assays.
- Experience in preparing basic formulations and dosing solutions is essential.
- Understands and implements study protocols according to AAALAC and other guidelines.
- Ability to work collaboratively within a team, provide and receive technical assistance to/from others in a wide range of laboratory-based activities/techniques, while displaying strong organizational and timely record-keeping skills.
- Interpersonal skills conductive to strong team integration and willingness to learn new techniques are essential.
- Ability to multi-task and perform work with a high degree of attention to detail while supporting programs in a fast-paced environment.
- Requires occasional weekend hours.
- Must have excellent observational and analytical skills, strong organizational skills, and significant hands-on laboratory experience.
- Excellent oral and written communication skills, is preferred. Experience working in an FDA-regulated environment is highly desired.
We are an Equal Opportunity Employer and do not discriminate against applicants due to race, ethnicity, gender, veteran status, or on the basis of disability or any other federal, state or local protected class. Nektar Therapeutics will consider for employment qualified applicants with criminal histories in the manner proscribed by the San Francisco Fair Chance Ordinance.
Company
Nektar Therapeutics is a research-based development stage biopharmaceutical company that discovers and develops innovative medicines in areas of high unmet medical need. Our R&D pipeline of new investigational drugs includes treatments for cancer and auto-immune disease. We leverage Nektar's proprietary and proven chemistry platform in the discovery and design of our new drug candidates. Our success is rooted in four key elements: our track record reflected by a portfolio of successful approved medicines which emanated from our chemistry platform and are made available globally by our pharmaceutical partners, our unique research and development pipeline of new investigational medicines in cancer and immunology, our proprietary and proven science and technology approach that fuels our discovery efforts and our team of dedicated scientists, clinicians and employees focused on bringing new medicines to patients with debilitating diseases.
Stock Symbol: NKTR
Stock Exchange: NASDAQ
- Website
- http://www.nektar.com/
- Phone
- 415-482-5300
- Location
-
455 Mission Bay Blvd South
San Francisco
California
94158
United States
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