Research Associate, Analytical Development

Thank you for your interest in a career at Senti Biosciences. Our mission is to create a new generation of smarter medicines that outmaneuver complex diseases in ways previously inconceivable. We are passionate about designing gene circuits to improve the "intelligence" of cell and gene therapies in order to enhance their therapeutic effectiveness against a broad range of diseases that conventional medicines are unable to address.

At Senti, we find purpose and meaning knowing that our efforts have the potential to improve the lives of patients and their families with more effective and safer treatment options. With science as our foundation and empathy as our key guiding principle, colleagues become friends, managers become mentors, and with time, cancer becomes history.

Summary: Senti Bio is seeking a highly motivated and experienced individual with a strong background in Analytical Development and testing of Cell and Gene therapies. The successful candidate will contribute to the advancement of Senti's proprietary immunotherapeutic cell engineering platforms focused on genetically modified cellular therapies. The candidate will work closely with Technical Operations and Research and Development, to advance the development of gene therapy products from research to the clinic. This role will be key in supporting research and pre-clinical studies, and the characterization of manufacturing and viral vector processes, driving pipeline from proof of concept to clinical scale manufacturing. Additionally, supporting assay development for early stage projects. Senti is looking for someone with a wide range of technical skills, the ability and want to learn new skills, and can perform experiments, organize and analyze results in a timely manner.

Responsibilities

• Learn Senti's platform assays to supporting process development and viral vector core.
• Support assay development for various platform technologies
• Support method Qualifications
• Provide testing support for Research & Development groups
• Write Test Methods and SOPs
• Independently perform experiments, organize and analyze results
• Successfully execute and document laboratory procedures and experiments with great attention to detail
• Other duties as assigned

Qualifications

• Bachelor or master's degree in Cell Biology or related life science field
• A minimum of 2 years of relevant experience, industry experience is strongly preferred
• Experience with Cell and Gene therapies
• Strong technical background with experience in one of the following areas; flow cytometry, ELISA, and qPCR-based assays
• Experience with mycoplasma testing is a plus
• Experience with cell culture
• Ability to multitask and meet deadlines in a fast-paced environment
• Ability to think critically and demonstrate troubleshooting and problem-solving skills
• Must be a team player, proactive and willing to work in a small team environment
• Must have excellent verbal and written communication skills
• Proficient with MS office and other commonly used software and technology platforms
• Self-motivated and eager to take on temporary responsibilities outside of initial job description

Salary and Benefits

• Base pay and stock options to be determined based on application qualifications with the aim of being competitive with similar roles in the area
• Significant growth opportunity as the company expands

Senti Bio is a leading gene circuit company designing gene circuits to create a new generation of "smarter medicines" and enhance the therapeutic effectiveness of cell and gene therapies against a broad range of diseases that are unaddressed by current standards of care. We are proud to count Leaps by Bayer, NEA, 8VC, Matrix Partners China, Mirae Asset Capital, Amgen Ventures, Intel Capital, Ridgeback Capital, Lux Capital, KB Investment, Pear VC, Smilegate Investment, Menlo Ventures, LifeSci Venture Partners, Alexandria Venture Investments, Allen & Company, LifeForce Capital, Omega Funds, Nest.Bio, Gaingels, Noveus Capital, and Goodman Capital among our investors. Senti Bio is based in South San Francisco, CA, USA.