Principal Scientist - Computational Protein Scientist

Thousand Oaks, CA
Jul 10, 2021
Required Education
Bachelors Degree
Position Type
Full time


If you feel like youre part of something bigger, its because you are. At Amgen, our shared missionto serve patientsdrives all that we do. It is key to our becoming one of the worlds leading biotechnology companies. We are global collaborators who achieve togetherresearching, manufacturing, and delivering ever-better products that reach over 10 million patients worldwide. Its time for a career you can be proud of. Join us.

Principal Scientist - Computational Protein ScientistLive

What you will do

Lets do this. Lets change the world. We are currently seeking a team leader for our computational protein engineering team at our headquarter campus in Thousand Oaks, CA. The candidate should have strong expertise and proven accomplishments in computational and machine learning studies for proteins and protein engineering. In this vital role you will lead a small team of computational scientists and data engineers in support of broad biologics discovery and optimization at Amgen. The goal is to apply the most effective computational methods, including structural modeling, machine learning, and data science techniques to advance our biologics drug discovery programs, spanning multiple modalities including therapeutic proteins, antibodies, and various bispecific and conjugate molecules.


What we expect of you

We are all different, yet we all use our unique contributions to serve patients. The qualified professional we seek is a scientist with these qualifications.

Basic Qualifications:

Doctorate degree with 3 years of industrial experience


Masters degree and 6 years of industrial experience


Bachelors degree and 8 years of industrial experience

Preferred Qualifications:
  • PhD. in computational biophysics or related fields
  • Strong track record of research accomplishment with five or more scientific publications or conference presentations in the area of computational protein modeling and engineering
  • Strong and broad experience in antibody modeling and engineering in an industrial setting
  • Proficient with one or more protein modeling software packages (MOE, Schrodinger, Rosetta, etc.)
  • Strong experience in applying machine learning to study proteins
  • Proficient in computer programming and scripting
  • Strong communication skills and enthusiasm for working in an interdisciplinary team environment

What you can expect of us

As we work to develop treatments that take care of others, so we work to care for our teammates professional and personal growth and well-being.

  • Vast opportunities to learn and move up and across our global organization
  • Diverse and inclusive community of belonging, where teammates are empowered to bring ideas to the table and act
  • Generous Total Rewards Plan comprising health, finance and wealth, work/life balance, and career benefits
Apply now

for a career that defies imagination

In our quest to serve patients above all else, Amgen is the first to imagine, and the last to doubt. Join us.

Equal Opportunity Statement

Amgen is an Equal Opportunity employer and will consider you without regard to your race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, or disability status.

We will ensure that individuals with disabilities are provided a reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. Please contact us to request an accommodation.

Join Us

If you're seeking a career where you can truly make a difference in the lives of others, a career where you can work at the absolute forefront of biotechnology with the top minds in the field, you'll find it at Amgen.

Amgen, a biotechnology pioneer, discovers, develops and delivers innovative human therapeutics. Our medicines have helped millions of patients in the fight against cancer, kidney disease, rheumatoid arthritis and other serious illnesses.

As an organization dedicated to improving the quality of life for people around the world, Amgen fosters an inclusive environment of diverse, ethical, committed and highly accomplished people who respect each other but compete intensely to win. Together, we live the Amgen values as we continue advancing science to serve patients.

Amgen is an Equal Opportunity employer and will consider all qualified applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, or disability status.