Scientst - Bioanalysis

South San Francisco, CA
Jul 08, 2021
Required Education
Position Type
Full time


Youve earned your degree. How will you use that achievement to reach your goals? Do more with the knowledge youve worked hard to acquire and the passion you already have. At Amgen, our shared missionto serve patientsdrives all that we do. It is key to our becoming one of the worlds leading biotechnology companies, reaching over 10 million patients worldwide. Become the professional you are meant to be in this meaningful role.



What you will do

Lets do this. Lets change the world. In this vital role you will work in a team environment to characterize the absorption, distribution, metabolism, excretion and pharmacokinetic properties of therapeutic drug candidates to achieve their full pharmacological potential.

Job Description

The department of pharmacokinetics and drug metabolism (PKDM) within Amgen is dedicated to the discovery and development of novel effective, safe medicines. PKDM works in close partnership with disciplines such as medicinal chemistry, pharmacology, toxicology, pharmaceutical sciences, clinical pharmacology and regulatory to design promising clinical therapeutic candidates, conduct preclinical development studies, support clinical evaluation and contribute to IND and NDA filings.

The responsibilities of a PKDM Scientist are to develop and routinely employ LC-MS based bioanalytical methods for the quantitative and qualitative analysis of protein biotherapeutics (i.e. antibodies, BiTE. fusion proteins etc.), endogenous proteins (i.e. biomarkers, protein targets, etc.) and small molecules in plasma, tissues, and other biological matrices to support pharmacokinetic and pharmacodynamics analysis. The role will require data interpretation and communication to project team representatives in support of drug discovery and development.

The ideal candidate will have a proven ability to execute experiments to quantitate protein/peptide and small molecules by LC-MS in support of both drug discovery and early development programs. This role requires capabilities of performing bioanalysis and solving bioanalytical technical challenges, a solid understanding of LC-MS technique and sample preparation workflow, and the ability to work collaboratively in a fast-paced work environment. The candidate will work as a member of the mass spectrometry group within PKDM and will be responsible for performing bioanalysis from sample preparation, LC-MS analysis to data interpretation. Other responsibilities will include instrument maintenance and troubleshooting, performing biochemistry experiments, electronic laboratory notebook keeping and communication of results to project teams.

What we expect of you

We are all different, yet we all use our unique contributions to serve patients. The scientific professional we seek is a teammate with these qualifications.

Basic Qualifications

  • Doctorate degree with 0-1 years of experience

  • Experience with operation, troubleshooting, and data interpretation of LC-MS is required.

Preferred Qualifications

  • Candidates for PKDM- bioanalysis position have a PhD or MS in chemistry, biochemistry, or equivalent.

  • Experience with automated liquid sample handling instruments and immunoaffinity capture is a plus.

  • The candidate should possess excellent oral and written communication skills and be able to excel in a highly collaborative, matrixed team environment.


Some of the vast rewards of working here

As we work to develop treatments that take care of others, so we work to care for our teammates professional and personal growth and well-being.

  • Full support and career-development resources to expand your skills, enhance your expertise, and maximize your potential along your career journey

  • A diverse and inclusive community of belonging, where teammates are empowered to bring ideas to the table and act

  • Generous Total Rewards Plancomprising health, finance and wealth, work/life balance, and career benefitswith compensation and benefits rated above 4 stars (out of 5) on Glassdoor

Apply now

for a career that defies imagination

Objects in your future are closer than they appear. Join us.

Equal Opportunity Statement

Amgen is an Equal Opportunity employer and will consider you without regard to your race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, or disability status.

We will ensure that individuals with disabilities are provided a reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. Please contact us to request an accommodation.

Join Us

If you're seeking a career where you can truly make a difference in the lives of others, a career where you can work at the absolute forefront of biotechnology with the top minds in the field, you'll find it at Amgen.

Amgen, a biotechnology pioneer, discovers, develops and delivers innovative human therapeutics. Our medicines have helped millions of patients in the fight against cancer, kidney disease, rheumatoid arthritis and other serious illnesses.

As an organization dedicated to improving the quality of life for people around the world, Amgen fosters an inclusive environment of diverse, ethical, committed and highly accomplished people who respect each other but compete intensely to win. Together, we live the Amgen values as we continue advancing science to serve patients.

Amgen is an Equal Opportunity employer and will consider all qualified applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, or disability status.

Amgen will consider for employment qualified applicants with criminal histories in a manner consistent with the San Francisco Fair Chance Ordinance.