Sr. Research Scientist II (EHR RWE Focused), Molecular Epidemiology, Biomarker Sciences

Location
Foster City, CA, United States
Posted
Jul 06, 2021
Ref
2214121
Required Education
Bachelors Degree
Position Type
Full time
Sr. Research Scientist II (EHR RWE Focused), Molecular Epidemiology, Biomarker Sciences
United States - California - Foster City

Gilead Sciences, Inc. is a research-based bio-pharmaceutical company that discovers, develops and commercializes innovative medicines in areas of unmet medical need. With each new discovery and investigational drug candidate, we seek to improve the care of patients living with life-threatening diseases around the world. Gilead's therapeutic areas of focus include HIV/AIDS, liver diseases, cancer and inflammation, and serious respiratory and cardiovascular conditions.

Making an impact on a global scale
Inclusion is one of the company's five core values. That's because we know that we are stronger and more innovative at Gilead when we are informed by a diverse set of backgrounds, experiences and points of view. Gilead Sciences is a biopharmaceutical company that discovers, develops and commercializes innovative therapeutics in areas of unmet medical need. The company's mission is to advance the care of patients suffering from life-threatening diseases worldwide.

When you join Gilead, you join our mission to change the world by enabling people to live healthier and more fulfilling lives. Come join a mission-driven bio-pharmaceutical organization that values inclusion and diversity, has a strong portfolio of products, and is constantly #CreatingPossible

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The Biomarker Sciences department at Gilead is dedicated to conduct biomarker and translational research to further understanding of specific aspects of biology, inform research, development and pipeline decisions, and advance the effectiveness of available therapies in appropriate patient populations. The Molecular Epidemiology team supports biomarker activities by integrating real-world data and epidemiologic evidence within the biomarker discovery and development strategy.

The Senior Research Scientist II, under the supervision of Molecular Epidemiology head within the Biomarker Sciences, will be responsible for design and conduct of epidemiology studies using observational and clinico-genomic databases. The position is expected to work across therapeutic areas that include oncology, virology, and immunology.

Responsibilities: Responsibilities will include, but not limited to, the following:
  • To lead epidemiologic studies from 'conception to completion' using large administrative and electronic health records (EHR) data including clinico-genomic and specialized EMR data to support biomarker and drug development activities. This would include design, protocol development, implementation, vendor management, and collaboration with other functions.
  • To work collaboratively on multi-functional projects and interact with biomarker scientists and scientists from other functions including clinical pharmacology, biology, bioinformatics, clinical research, and clinical data science on a regular basis.
  • To conduct studies to inform dosing, early toxicity concerns, drug-drug interactions, and other PK/PD parameters for molecules under development.
  • To initiate solution-driven projects to help understand outstanding scientific questions related-to drug and biomarker discovery and development.
  • To work with biomarker therapeutic area heads and other biomarker scientists and clinical pharmacology colleagues to integrate real-world data and epidemiologic approach into product or program specific biomarker strategy and clinical pharmacology activities.
  • To serve as a subject matter expert and cross functional resource for epidemiology and real-world data.
  • To represent Biomarker Sciences in internal and external collaborative projects and bring insights in design and analysis of data from an epidemiologic perspective.
  • To contribute significantly in strategy and functional development of Molecular Epidemiology team. Provide scientific oversight and mentor junior members of the team, fellows and interns.
  • To effectively communicate study findings through internal presentations, authoring conference abstracts and manuscripts for publication in peer reviewed journals.


Qualifications:
  • Candidates should have a PhD in epidemiology, public health or other relevant fields with at least 5-7 years of post-degree experience in pharma/biotech or related research organizations/academia.
  • Should have experience in conducting studies using large observational and/or multi-omics database and/or experience in conducting molecular epidemiology studies.
  • Should have proficiency with statistical software (SAS, R, etc.) and programming. Experience in applying novel analytical or computational (machine learning) technique and data science expertise to integrate and mine large complex data is a plus.
  • Candidates are expected to have familiarity with large healthcare databases including electronic health records, specialized EMR databases, and claims data. Knowledge of clinico-genomic and publicly available genomic databases (e.g., TCGA) is a plus.
  • Should have general knowledge of drug discovery and development process.
  • Should have good oral and written communication skills demonstrated by a track record of publication(s) in major scientific journals and presentations in national or international conferences.
  • Candidates are expected to have the ability to work mostly independently. Experience in leadership roles or demonstrated leadership skill will be an advantage.
  • Candidates are expected to work in a diverse, collaborative cross-functional environment and are expected to lead or co-lead multiple projects simultaneously and to hold broader companywide vision beyond individual responsibilities.

Travel may be required up to 5-10% of time for this position.
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As an equal opportunity employer, Gilead Sciences Inc. is committed to a diverse workforce. Employment decisions regarding recruitment and selection will be made without discrimination based on race, color, religion, national origin, gender, age, sexual orientation, physical or mental disability, genetic information or characteristic, gender identity and expression, veteran status, or other non-job related characteristics or other prohibited grounds specified in applicable federal, state and local laws. In order to ensure reasonable accommodation for individuals protected by Section 503 of the Rehabilitation Act of 1973, the Vietnam Era Veterans\' Readjustment Act of 1974, and Title I of the Americans with Disabilities Act of 1990, applicants who require accommodation in the job application process may contact careers@gilead.com for assistance.

For more information about equal employment opportunity protections, please view the 'EEO is the Law' poster.

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YOUR RIGHTS UNDER THE FAMILY AND MEDICAL LEAVE ACT

PAY TRANSPARENCY NONDISCRIMINATION PROVISION

Our environment respects individual differences and recognizes each employee as an integral member of our company. Our workforce reflects these values and celebrates the individuals who make up our growing team.

Gilead provides a work environment free of harassment and prohibited conduct. We promote and support individual differences and diversity of thoughts and opinion.
For Current Gilead Employees and Contractors:
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