Research Associate - Assay Development

Brisbane, CA, United States
Jul 05, 2021
Biotech Bay
Required Education
Bachelors Degree
Position Type
Full time

Mammoth Biosciences, Inc. is harnessing the diversity of nature to power the next-generation of CRISPR products. Through the discovery and development of novel CRISPR systems, the company is enabling the full potential of its platform to read and write the code of life. By leveraging its internal research and development and exclusive licensing to patents related to Cas12, Cas13, Cas14 and CasPhi, Mammoth Biosciences can provide enhanced diagnostics and genome editing for life science research, healthcare, agriculture, biodefense and more. Mammoth is democratizing disease detection with easy and affordable point-of-care tests that allow real-time and simultaneous detection of multiple conditions, along with high-throughput tests that allow for unprecedented testing volume. Further, the company is transforming disease treatment with its proprietary micro-sized CRISPR proteins that enable new editing and delivery options. Based in Brisbane, CA, Mammoth Biosciences is co-founded by CRISPR pioneer and Nobel Prize winner Jennifer Doudna and principal founders Trevor Martin, Janice Chen, and Lucas Harrington. The firm is backed by top institutional investors including Decheng, Mayfield, NFX, and 8VC, and leading individual investors including Brook Byers, Tim Cook, Bob Nelsen, and Jeff Huber.


Mammoth is seeking a Research Associate, Assay Development experienced in protein and nucleic acid biochemistry techniques to support our research and product development teams. The ideal candidate will have experience in nucleic acid extraction, amplification and detection methods and techniques. The candidate will also have experience in handling a variety of human clinical sample types and experience with laboratory processes involving clinical samples. Furthermore, the candidate will be comfortable working as part of a team, be highly motivated, and display excellent time management skills.

    • Contribute to CRISPR-based diagnostics assay optimization and reagent formulation development
    • Conduct experiments for sample processing, nucleic acid extraction, amplification, and related assays
    • Conduct clinical sample processing and testing on CRISPR-diagnostic assay in BSL 2+ laboratory
    • Participate in verification and validation studies
    • Perform data analysis of experiments and generate summaries for group meetings
    • Document information by maintaining lab notebooks and equipment record books
    • Resolve problems by examining and evaluating data and selecting corrective steps
    • Complete projects by assisting project team and attending and presenting in group and project meetings
    • Maintain quality compliance by participating in training and implementing approved quality procedures

    • Bachelor's in biology, chemistry or a related field
    • 2+ years industry experience in molecular biology and biochemistry
    • Experience processing different human sample types
    • Experience with designing and optimizing nucleic acid amplification (e.g. qPCR) and/or other molecular biology protocols

    • Experience with in vitro CRISPR cis and trans cleavage assays
    • Desire to work with infectious human samples
    • Ability to independently design, optimize and troubleshoot experiments
    • Exceptional skills in communication, presentation, data analysis, and interpretation
    • Highly motivated and detail-oriented with the ability to think creatively towards efficient problem solving

    • Company-paid health/vision/dental benefits
    • Unlimited vacation and generous sick time
    • Company-sponsored meals and snacks
    • Wellness, caregiver and ergonomics benefits
    • 401(k) with company matching

It is our policy and intent to provide equal opportunity to all persons without regard to race, color, religion, political affiliation, sex/gender (including gender expression/identity, pregnancy, childbirth and related medical conditions), marital status, registered domestic partner status, sexual orientation, age, ancestry, national origin, veteran status, disability, medical condition, genetic characteristics, and/or any other basis protected by law. This policy covers all facets of employment including, but not limited to: recruitment, selection, placement, promotions, transfers, demotions, terminations, training, and compensation.