Process Development Scientist - Pivotal Bioprocesses Sciences & Technologies

HOW MIGHT YOU DEFY IMAGINATION?

Youve earned your degree. How will you use that achievement to reach your goals? Do more with the knowledge youve worked hard to acquire and the passion you already have. At Amgen, our shared missionto serve patientsdrives all that we do. It is key to our becoming one of the worlds leading biotechnology companies, reaching over 10 million patients worldwide. Become the professional you are meant to be in this meaningful role.

Process Development Scientist - Pivotal Bioprocesses Sciences & Technologies

Live

What you will do

Lets do this. Lets change the world. In this vital role you will be responsible for development, characterization, scale-up and support of drug substance processes to enable commercial advancement of programs from Ph II/III clinical trials to marketing application. The Process Development Scientist will report to the Process Development Principal Scientist in an integrated group in which cell culture and purification scientists work together to advance Amgens rich, exciting and dynamic pipeline. With Amgens biology first approach, the position provides the unique opportunity of being able to work on multiple modalities from antibodies and oncolytic viruses to bispecifics and siRNAs.

The Pivotal Drug Substance Process Development organization at Amgen develops, characterizes and supports the commercialization of the drug substance manufacturing processes for all late-stage programs across the Amgen portfolio.

Role Responsibilities:

• Apply established platform approaches and utilize solid problem-solving skills to rapidly solve drug substance challenges and build robust processes with efficient experimentation

• Drive new approaches and utilize out-of-the-box thinking to contribute to technology development

• Demonstrate the desire to expand and develop skills in cell culture and purification, thereby further contributing to the integrated group

• Participate in drug substance teams and collaborate cross functionally with analytical and drug product representatives to deliver drug substance manufacturing processes in a phase appropriate manner.

• Deliver process amenable to cGMP operation and carry out results of drug substance in a cGMP manufacturing environment

• Ability to execute projects as part of a team

• Proven collaborative experience and ability to optimally work through others

• Author, or provide direction for the authorship of, technical report or CMC regulatory submissions which may require minimal additional editing

• Give presentations within the department and to senior management with

• Actively create, generate, and present paper/presentations at scientific meetings

• Well-recognized in the scientific community through a sustained record of peer-reviewed publications and patents

Win

What we expect of you

We are all different, yet we all use our unique contributions to serve patients. The scientist professional we seek is a self-starter with these qualifications.

Basic Qualifications:

Doctorate degree (by September 2021)

OR

Masters degree & 4 years of scientific experience

OR

Bachelors degree & 6 years of scientific experience

Preferred Qualifications:

• Doctorate in Chemical Engineering, Biochemical Engineering, or other relevant sciences

• Consistent track record of problem solving and trouble-shooting protein drug substance purification processes, preferably in a process development environment

• Strong understanding and extensive hands-on experience in protein chromatography, including affinity, ion exchange, and hydrophobic interaction chromatography

• Experience in filtration operations, including ultrafiltration/diafiltration (UF/DF)

• Understanding of protein characteristics and critical attributes to direct product/process control strategies

• Ability to independently identify, develop and implement scientific solutions to practical problems.

• Motivated self-starter with excellent interpersonal and organizational skills

• Leadership experience of progressively increased scope and ability to encourage and lead a group of scientists to deliver on sophisticated and ambitious objectives in defined timelines

• Demonstrated eminence in the scientific community through a sustained record of peer reviewed publications

• Excellent verbal communication and scientific writing skills

• Demonstrated success working with diverse team members in a dynamic, cross-functional environment

• Familiarity with design of experiments and statistical analysis of data

• Knowledge of license application and the drug development process

• Exposure to cGMP manufacturing and CMC components of regulatory submissions

Thrive

Some of the vast rewards of working here

As we work to develop treatments that take care of others, so we work to care for our teammates professional and personal growth and well-being.

• Full support and career-development resources to expand your skills, enhance your expertise, and maximize your potential along your career journey

• A diverse and inclusive community of belonging, where teammates are empowered to bring ideas to the table and act

• Generous Total Rewards Plancomprising health, finance and wealth, work/life balance, and career benefitswith compensation and benefits rated above 4 stars (out of 5) on Glassdoor

Apply now

for a career that defies imagination

Objects in your future are closer than they appear. Join us.

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Equal Opportunity Statement

Amgen is an Equal Opportunity employer and will consider you without regard to your race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, or disability status.

We will ensure that individuals with disabilities are provided a reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. Please contact us to request an accommodation.

Join Us

If you're seeking a career where you can truly make a difference in the lives of others, a career where you can work at the absolute forefront of biotechnology with the top minds in the field, you'll find it at Amgen.

Amgen, a biotechnology pioneer, discovers, develops and delivers innovative human therapeutics. Our medicines have helped millions of patients in the fight against cancer, kidney disease, rheumatoid arthritis and other serious illnesses.

As an organization dedicated to improving the quality of life for people around the world, Amgen fosters an inclusive environment of diverse, ethical, committed and highly accomplished people who respect each other but compete intensely to win. Together, we live the Amgen values as we continue advancing science to serve patients.

Amgen is an Equal Opportunity employer and will consider all qualified applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, or disability status.