R&D Associate, Histology

Tarrytown, New York, United States of America
Jul 04, 2021
Required Education
Bachelors Degree
Position Type
Full time
We are seeking a creative, collaborative, detail oriented, and highly organized individual to help build and support a brand-new Preclinical Histology Core that will serve all therapeutic areas in Research. This core facility will use groundbreaking histotechnologies, automation, imaging instruments, and software platforms to provide full services for histology, histochemistry, immunohistochemistry (IHC), and in situ hybridization (ISH) experiments on non-human tissues. This facility will also develop novel methods to power exploratory research including highly multiplexed IHC/ISH staining techniques, 3D histology, and image data repositories to power quantitative analyses and machine learning data mining efforts.

We are looking for a candidate who will work closely with members of the team to deliver high quality, meticulous, and unbiased experimental data, interpretations, and novel methods in support of Regeneron's diverse therapeutic programs.

In this role, a typical day may include:
  • Supervised and independent execution of experiments planned with the histology group.
  • Handling small animals including euthanasia followed by intracardial perfusion and dissection for tissue harvesting.
  • Experimental animal tissue dissection & sample preparation; paraffin and cryo sectioning; histochemical stainings.
  • Development of histological techniques including new tissue preparations, development of new staining protocols, optimization across multiple tissue types.
  • Lab operations including organization and order of materials and reagents required for studies and maintenance of histology equipment, as well as online and physical records of data.
  • Documentation and accurate storage of hazardous materials.
  • Working closely with team members to coordinate and troubleshoot multiple experiments, accommodate changing priorities and timelines, and provide updates on the progress of projects.
This role may be for you if you have:
  • Shown history of executing and accomplishing histology experiments in a timely and independent manner.
  • Strong communication and social skills, with the ability to work independently and collaboratively as part of a larger project within a team-first environment.
  • A passion for biology and helping others and a dedication to share, collaborate, and lift up others.
  • Outstanding attention to detail, and due diligence in project execution.

To be considered for this role, you must have minimum of a Bachelor's degree in science and at least 2 years of shown experience. You should have extensive knowledge of vertebrate anatomy and be able to perform tissue dissections. We would like candidates to have experience in basic histological techniques such as fixation, cryo or paraffin sectioning, and basic tissue stains. Experience with immunolabeling, specialized sectioning and staining is a plus.