Life Science Database Manager/Programmer

Seattle, WA, United States
Jul 02, 2021
Required Education
Bachelors Degree
Position Type
Full time
Life Science Database Manager/Programmer

This position will support the small molecule/drug discovery team by managing data and improving information transfer between research groups by integrating/streamlining information systems from various workflows.

Good things are happening at Omeros!

Come join our Discovery Team!

Who is Omeros?

Omeros is a commercial-stage biopharmaceutical company committed to discovering, developing and commercializing small-molecule and protein therapeutics for large-market and orphan indications targeting inflammation, complement-mediated diseases, disorders of the central nervous system and immune-related diseases, including cancers. In addition to its commercial product OMIDRIA (phenylephrine and ketorolac intraocular solution) 1%/0.3%, Omeros has multiple phase 3 and phase 2 clinical-stage development programs focused on complement-mediated disorders and substance abuse. Omeros also has a diverse group of preclinical programs including GPR174, a novel target in immuno-oncology that modulates a new cancer immunity axis recently discovered by Omeros. Small-molecule inhibitors of GPR174 are part of Omeros' proprietary G proteincoupled receptor (GPCR) platform through which it controls 54 new GPCR drug targets and their corresponding compounds. The company also exclusively possesses a novel antibody-generating platform.

What are your job responsibilities?

  • Manage in-house and cloud-based database systems
  • Create and maintain software scripts for data processing, analysis and management
  • Interface with medicinal and computational chemistry, structure-based drug discovery, discovery biology, and preclinical functions
  • Coordinate and establish data system governance and policies
  • Adhere to internal IT policies, including data security and data life cycle management
What education and experience do you need?

  • BS/MS degree with demonstrated experience of working with data and software as it pertains to the drug discovery industry.
  • Data management experience including:
    • Managing in-house and cloud-based data pipelines
    • Implementing, querying and maintenance of databases
    • Scripting and configuring database software systems; for instance, scripting custom auxiliary code for systems to manipulate, reformat and manage new and legacy data and databases
    • Working with databases (i.e. Access, SQL Server, Oracle, etc.), hands-on experience with ActivityBase and/or Live Design is a plus
    • Programming with Visual Basic for Applications in MS Excel, Python or other scripting languages
    • Finding custom/vendor-offered solutions for automated data handling, data analysis and reporting
    • ELNs, LIMS or custom life science database systems for efficiently moving data between groups
    • Working with APIs to seamlessly move data between various databases/applications
  • Interfacing with chemists, biologists and IT teams
  • Working knowledge of high-throughput screening, data analysis and presentation is a plus
  • Fundamental understanding of biology/chemistry as it relates to (bio)chemical reactions, assay readout data formats and chemistry-related software
  • Ability to batch register and reformat electronic compound libraries is a plus
  • Demonstrated working knowledge of chemical structure representations and history of successfully interfacing with functions in drug discovery organizations
  • Good interpersonal and communication skills, both written and verbal
  • Detail orientation
Behavioral Competencies Required:

  • A willingness to work with other team members, share and encourage new ideas, strive to find the best solutions and build team competencies over time
  • A good understanding of the goals and longer-term direction
  • An eye toward self-improvement, productivity and gaining knowledge
Supervisory Responsibilities:

  • This position may or may not have supervisory responsibilities
  • Carry out supervisory responsibilities in accordance with the organization's policies and applicable laws
  • Responsibilities include interviewing, hiring, and training employees; planning, assigning, and directing work; appraising performance; rewarding and disciplining employees; addressing complaints and resolving problems
Physical Demands Required:

  • Intermittent physical activity including bending, reaching, pushing, pulling, or lifting up to 20 lbs.
  • May encounter prolonged periods of sitting or standing
  • This position requires working around hazardous materials
Omeros is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to status as a protected veteran or a qualified individual with a disability, or other protected status such as race, religion, color, national origin, sex, age, marital status, or any other factor determined to be unlawful by federal, state, or local statutes.

It is our policy to provide reasonable accommodation to anyone with a disability who needs assistance completing the job application process. If you need assistance, you can either send an e-mail to or contact Omeros, asking for Human Resources, at (206) 676-5000