Amgen

Postdoctoral Fellow - Discovery Attribute Sciences

Employer
Amgen
Location
Thousand Oaks, CA
Posted
Jul 02, 2021
Ref
R-123023
Required Education
Doctorate/PHD/MD
Position Type
Full time

HOW MIGHT YOU DEFY IMAGINATION?

Do more with the knowledge youre working hard to acquire and the passion you already have. At Amgen, our shared missionto serve patientsdrives all that we do. It is key to our becoming one of the worlds leading biotechnology companies, reaching over 10 million patients worldwide. Through this program, you will acquire the valuable hands-on skills and foundational experience to become the professional you are meant to be in your chosen field.

Postdoctoral Fellow Discovery Attribute Sciences

Live

This could be your everyday

Lets do this. Lets change the world. During this program, you will be provided with an enriching environment to inspire innovation that will contribute to the development of human therapeutics.

We have an exciting opportunity for a highly motivated postdoc in the Discovery Attribute Sciences Department at Amgen. The focus of this role is to develop methodologies for characterizing key steps involved in the heterobifunctional molecule (i.e., PROTAC) induced protein degradation. This research endeavor will encompass multiple biophysical techniques including surface plasmon resonance (SPR), isothermal calorimetry (ITC), nuclear magnetic resonance (NMR), to understand complex relationships between molecular recognition of PROTAC-mediated ternary complexes and targeted degradation. The ideal candidate should have a Ph.D. in biophysics, biochemistry, chemical biology or related fields. Background in protein NMR spectroscopy, experience with cell-free protein expression and isotope or paramagnetic tag labeling are highly desirable. The successful candidate will have a unique opportunity to interact with Amgen scientists across all research areas, work on state-of-the-art instruments and publishing their work.

The postdoctoral position is for 3 years with the option to extend for an additional year.

Win

Heres what it takes to Win

We are all different, yet we all use our unique contributions to serve patients. The dedicated individual we seek is a scientist with these qualifications.

Basic qualifications

  • PhD at the time of appointment

Preferred qualifications

  • PhD in [biophysics, biochemistry, chemical biology or related fields]

  • Protein NMR spectroscopy, protein-protein interaction, protein structure and model refinement

  • Motivated self-starter, capable of working independently, excellent oral and written communication skills, and enjoy working in a collaborative environment

Our culture is what makes Amgen a special place to work. We have a powerful shared purpose around our mission to serve patients. We respect one another, recognize contributions, and have embedded collaboration, trust, empowerment, and inclusion in all that we do.

Thrive

Some of the vast rewards of working here

As we work to develop treatments that take care of others, so we work to care for our teammates professional and personal growth and well-being.

  • Full support and career-development resources to expand your skills, enhance your expertise, and maximize your potential along your career journey

  • A diverse and inclusive community of belonging, where teammates are empowered to bring ideas to the table and act

  • Generous Total Rewards Plancomprising health, finance and wealth, work/life balance, and career benefitswith compensation and benefits rated above 4 stars (out of 5) on Glassdoor

Equal Opportunity Statement

Amgen is an Equal Opportunity employer and will consider you without regard to your race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, or disability status.

We will ensure that individuals with disabilities are provided a reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. Please contact us to request an accommodation.


Join Us

If you're seeking a career where you can truly make a difference in the lives of others, a career where you can work at the absolute forefront of biotechnology with the top minds in the field, you'll find it at Amgen.

Amgen, a biotechnology pioneer, discovers, develops and delivers innovative human therapeutics. Our medicines have helped millions of patients in the fight against cancer, kidney disease, rheumatoid arthritis and other serious illnesses.

As an organization dedicated to improving the quality of life for people around the world, Amgen fosters an inclusive environment of diverse, ethical, committed and highly accomplished people who respect each other but compete intensely to win. Together, we live the Amgen values as we continue advancing science to serve patients.

Amgen is an Equal Opportunity employer and will consider all qualified applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, or disability status.