Scientist- AAV

Location
92121, San Diego
Posted
Jun 29, 2021
Required Education
Doctorate/PHD/MD
Position Type
Full time

Responsibilities:

  • Setting, completing and updating milestones related to main project
  • Performing cell culture (adherent and suspension) for virus creation and purification
  • Developing and optimizing small and medium scale AAV production for scale up manufacturing
  • Performing researching into ways of enhancing AAV production
  • Oversight of CROs
  • Participation in transfer and validation activities for upstream production to CDMO
  • Performing standard and advanced cloning techniques
  • Executing experiments, independently and in conjunction with a small team in support of research and clinical applications
  • Following laboratory protocols and safety regulations
  • Performing detailed and accurate documentation of all experiments and laboratory practices
  • Accountable for on-time, high quality results and clearly communicating progress

Requirements:

  • Ph.D. in virology, biology, biochemistry, microbiology, biomedical engineering, bioengineering or related field required
  • Experience with AAV production or other biologic scale up production
  • Demonstrated prior experience with AAV or biologic production and the pain points associated
  • Aware of suspension AAV production and the areas that can be optimized
  • Ability to work independently as well as in a collaborative team environment
  • Strong work ethic, communication skills and goal-oriented personality
  • Preferred experience:
    • 2+ years of industry experience preferred.
    • Experience with suspension cell culture and protein production
    • Experience with flow cytometry, ELISAs, PCR, and microscopy
    • Proven ability to draft and implement lab protocols.