Principal Scientist, Production

Employer
Bachem
Location
Torrance, CA
Posted
Jun 28, 2021
Ref
647436201
Hotbed
Biotech Beach
Required Education
Doctorate/PHD/MD
Position Type
Full time

The Swiss based Bachem Group is a public, innovation-driven company specializing in the development and manufacturing of pepTides and oligonucleoTides. As a full service provider Bachem offers products for clinical development and commercial applications as well as a comprehensive catalog and exclusive custom synthesis. With 50 years of experience and subsidiaries in Switzerland, the United States, the United Kingdom and Japan, Bachem is the partner of choice for the biotech and pharma industry worldwide.
Bachem. Leading Partner in Tides

In order to continue our organic growth, we are constantly looking for talent.

The Principal Scientist in Production Department will work in a team manner to achieve goal-oriented solutions in development for optimizing and troubleshooting of production processes in Liquid Phase and/or Solid Phase-synthesis. This position will work in conjunction with the management of the production groups, will coordinate with other departments, and may lead/manage a team for assigned projects

Your Tasks:

  • Serve as subject matter expert for internal/external customers, and set clear timelines & goals for assigned projects; prioritize efforts to deliver on time; provide excellent customer experience
  • Plan and execute multiple projects in Production, and assign resources according to priorities and business requirements
  • Lead peptide and/or oligonucleotide API (active pharmaceutical ingredients) projects, including research, investigation, validation, and continuous production process improvement in Production Department
  • Timely update and report status/results of in-progress projects to the particular stakeholders; prepare technical reports; present outcome/results of projects with stakeholders
  • Maintain production quality by reducing backlog of open and aging quality records, including deviations, CAPAs, and customer commitments
  • Collaborate with cross-function departments to plan the necessary resources in order to guarantee a smooth and efficient execution of projects with optimized utilization of internal and external resources
  • Proactively monitor the trend of working techniques, purification technologies and production processes; advise and drive installation of production equipment, tools and chemical utilities
  • Support in planning and implementation of investment projects to achieve higher capacity, compliance, or new technologies; contribute to all capital expenditure activities as needed
  • Realize improvement opportunities for safety compliance and manufacturing process streamline; improve established processes with regards to cost, efficiency and safety
  • Follow good housekeeping in workplace; ensure GMP compliant operation in Production
  • Be responsible for production equipment/assets/facility; support for the related preventive maintenance
  • Support Production VP in technology transfers and business proposals
  • Recruit, coach, and supervise production staff to meet quality, quantity, and timeline requirements; identify and develop capable individuals to the first tier of supervisors (team leaders)

Required:

  • PhD Degree in Chemistry or a Science related field, 5+ years’ industry experience. A postdoc experience is a plus
  • Good knowledge of peptide/oligonucleotide chemistry
  • Minimum of 10 years in Organic Synthesis and its relevant purification
  • Strong understanding of production quality systems and cGMP regulations
  • Demonstrated resourcefulness, strategic and analytical thinking, directed toward achieving objectives
  • Market-focused and customer-focused with the ability to anticipate changes in needs and potential problems
  • Excellent written and oral communication skills; outstanding interpersonal skills
  • Excellent computer knowledge, including ChemDraw, Microsoft Word, Excel, and PowerPoint. Experience of Visio and Project is a plus
  • Ability to effectively organize, multitask, and work in a fast-paced, deadline driven work environment
  • Ability to communicate in a proactive and solution-focused manner, including keeping management aware of potential issues
  • Detail oriented with the ability to troubleshoot and resolve technical and analytical problems
  • Ability to work independently and manage one’s time
  • Communicate effectively and ability to function well in a team environment

Preferred:

  • Experience with Master Control and SAP
  • Industry experience
  • Understanding of GMP according to ICH Q7