Scientist II-III

Location
94538, Fremont
Posted
Jun 23, 2021
Required Education
Bachelors Degree
Position Type
Full time

Job Description

Eurofins DiscoverX Products, LLC is a leader in providing innovative solutions to the pharmaceutical industry by developing, manufacturing, and commercializing cell lines, cell-based assay kits, and supporting reagents.  The holder of this position will be responsible for development of new cell lines and bioassays to support product development and client-driven custom projects.

  • Responsible for manufacture and optimization of assay-ready cells to support development of custom bioassays for diverse DiscoverX assay formats.
  • Participates as one of several analysts to perform assay qualification of custom bioassays with client therapeutic agent, generating the required data within timelines defined by client
  • Reviews own assay qualification (or other experimental) results and confirms accuracy before submitting to supervisor / project lead for inclusion in study results / reports
  • Provides appropriate documentation and technical support for downstream users of custom bioassays including contribution of detailed protocols for user manuals, custom methods, and/ or client reports.
  • Provides detailed cell lot manufacturing / cell culturing information to operations team, and trains others to perform assay-ready cell manufacturing as needed
  • Performs new assay development as needed to facilitate rapid development of novel assays for Eurofins DiscoverX product portfolio or custom development projects
  • Presents results in both written and oral format and delivers data and/or reports to appropriate stakeholders within a multidisciplinary team environment in a timely fashion
  • Accurately documents experimental procedures and results in the ELN and stores data on appropriate secure data servers in accordance with company policy
  • Performs other duties as assigned to support the smooth functioning of shared laboratory spaces and equipment
  • Provides cross-functional support to other departments as required
  • Demonstrates and promotes the company vision
  • Owns the accountability and responsibility of delivering to client needs and timelines
  • Adjusts work hours as needed to meet client deadlines
  • Regular attendance and punctuality
  • Applies quality principles in all areas of responsibility, as appropriate
  • Conducts all activities in a safe and efficient manner, adhering to site employee health and safety (EHS) requirements

Qualifications

The ideal candidate would possess:

  • Experience with flow cytometry for characterization of surface markers strongly preferred
  •    Experience handling or  isolation/purification of immune cells (e.g. PBMCs, NK and CD4+ / CD8+ T cells) desirable
  •    Experience performing quantitative target cell killing assays (e.g. ADCC, CDC, and T- cell redirection) desirable
  •    Experience with data analysis packages such as SoftMaxPro/PLA module or PLA 3.0 for parallel line analysis strongly preferred

Basic Minimum Qualifications: 

  • BS/MS in cell biology, biochemistry, biotechnology or related field with a minimum of 6 years of industry experience.
  • Extensive mammalian cell culture expertise with including HEK, CHO and U2OS, as well as diverse cancer cell models
  •   Assay development expertise with various functional assay readouts (e.g.  cAMP, reporter gene assays, etc.)
  •   Experience running or developing bioassays for potency or lot release applications strongly preferred
  •    Experience with data analysis packages such as GraphPad Prism, Microsoft Powerpoint and Excel required
  •    Ability to work independently, efficiently and productively in a fast-paced, highly collaborative and diverse team environment.
  •    Eagerness to develop, learn and adopt new methods
  •    Strong collaborative and communication skills, proactive attitude and critical problem-solving abilities
  •    Must be detail oriented and consistent in experimental approach.
  •    Demonstrated written and verbal communication skills.
  • Highly organized, efficient and able to multitask.
  • Authorization to work in the United States indefinitely without restriction or sponsorship

Additional Information

Position is full-time, Monday - Friday 8:00am-5:00pm.  Candidates currently living within a commutable distance of Fremont, CA are encouraged to apply.

  • Excellent full time benefits including comprehensive medical coverage, dental, and vision options
  • Life and disability insurance
  • 401(k) with company match
  • Paid vacation and holidays

Eurofins is a M/F, Disabled, and Veteran Equal Employment Opportunity and Affirmative Action employer.