Senior Scientist - Vector Design and Cell Line Engineering

Location
Cambridge
Posted
Jun 14, 2021
Ref
5045891002
Required Education
Bachelors Degree
Position Type
Full time
JOB PURPOSE

Sana biotechnology is developing cutting-edge targeted in vivo gene therapies to provide cures for patients. We are looking for a creative and highly-motivated individual to join our Gene Therapy - Vector Design team, and help us advance our gene therapy pipeline through the development of new discovery platforms . This individual will join a dynamic, rapidly growing, and highly collaborative team that combines significant biologic drug discovery experience with pioneering discoveries driving a novel biological platform.

DUTIES AND RESPONSIBILITIES
  • Supervise and participate in the design, construction and testing of pooled selection strategies.
  • Collaborate with research functional leaders and program leaders to ensure that the selection strategies are designed and constructed to meet specifications, and communicate robustly with them throughout development.
  • Working closely with other members of the gene therapy, computational biology and process development teams to share and apply knowledge advancements.
  • Reviewing and presenting data cross-functionally at department meetings and larger forums.
  • Comply with standard laboratory practices and company policies, including strict notebook documentation and biosafety policies.
  • Contribute to the overall Sana mission and culture.

QUALIFICATIONS

Basic Qualifications
  • Ph.D. in Cell Biology, Synthetic Biology, Biophysics, Molecular Biology, Bioengineering or related discipline with a minimum of 5 years of directly related experience in academic research and/or biotech industry
  • Demonstrated proficiency in high-throughput pooled screening methods, including the generation of high-complexity combinatorial libraries
  • Skills in synthetic biology, genetic engineering or gene circuit design (knock-ins and knock-outs), cell biology, cloning and molecular biology
  • Excellent bench skills with attention to detail and high standards for data integrity and quality
  • Must be detail oriented, self-motivated, flexible, and able to prioritize and manage several fast-paced projects concurrently
  • Outstanding verbal and written communication skills for technical and non-technical audiences
  • Demonstrated ability to work in cross-functional teams as a strong team player as well as independently
  • Working safely in person on a predictable and regular in-person basis is an essential job function for this position and the Company requires that all individuals working in-person, subject to certain exceptions, be fully vaccinated against COVID-19

Preferred Qualifications
  • Experience working with barcoding systems and/or single cell analysis
  • Facility with one or more programming languages, such as R/Bioconductor or Python


To perform this job successfully, an individual must be able to perform each essential duty satisfactorily. The job description listed above is representative of the knowledge, skill, and/or ability required. Reasonable accommodations may be made to enable individuals with disabilities to perform the essential functions.

At Sana, we believe that a diverse workforce strengthens us as a company and helps us to achieve our mission to meaningfully change the outcome of many human diseases. This belief is a pillar of our business and is critical to our success. Our goal is that Sana is the place for talented people to bring their authentic selves to work, to have a great career and to deeply, positively impact patients.

The Company is committed to providing a workplace free of discrimination and harassment based on race, color, religion, age, gender, national origin, ancestry, physical or mental or sensory disability (including the use of a trained guide dog or service animal by a person with a disability), genetic information, actual or perceived HIV or Hepatitis C infection, medical condition (cancer or a record or history of cancer and genetic characteristics), marital status, sexual orientation, sexual preference, pregnancy (including childbirth and related medical conditions), disability, veteran status, political ideology, taking or requesting statutorily protected leave, status as a victim of domestic violence, sexual assault or stalking, or any other basis prohibited by applicable law.

Core to our values, we believe there is nothing more important than the health and wellness of you and your family. We cover 100% of the cost for employee health coverage and offer generous time-off, parental leave, short and long term disability, financial wellness programs, a 401(k) Plan, Employee Stock Purchase Plan, commuter subsidy and a variety of wellness offerings to support each person individually.