Research Associate, Histology

Redwood City, CA
Jun 14, 2021
Biotech Bay
Required Education
Bachelors Degree
Position Type
Full time
Adverum is currently seeking a Histologist candidate who is a highly motivated, passionate, experienced, energetic, and honest researcher who will support studies focused on evaluating mechanism and efficacy of drug candidates in gene therapy programs. The Microscopy and Histology group serves a core function for Adverum by supporting the multiple projects across our pipeline. Currently our emphasis is on combating ocular disease, with that, experience in ocular histology and anatomy is desired. Position title will be commensurate with experience.  
What you'll do:
  • Perform histology-related activities including tissue processing, embedding, sectioning (paraffin and cryo), staining, whole mount staining, and vibratome procedures.
  • Perform Immunohistochemistry, Immunofluorescence, and In-Situ hybridization labeling of tissues derived from preclinical and research studies.
  • Perform microscopy and imaging activities to support the groups core functions.
  • Support the various histology and microscopy core group functions.
  • Perform tissue dissections, grossing, and ex-vivo cultures.
  • Package and present data to departmental teams and project leads. 

About you:
  • Histotechnologist (HT/HTL) or BS in Biological Sciences, Pharmacology, or a related scientific discipline with 2+ years of experience; industry experience preferred.
  • Hands-on, bench-science expertise and understanding of antibody-labeling theory, protocols, and expected results.
  • Experience performing in-situ hybridization/RNA-Scope assays, both manual and automated.
  • Experience performing tissue dissection and tissue grossing to accommodate the needs of any project.
  • Experience automating IFL and IHC procedures.
  • Ex-vivo tissue culture experience
  • Excellent record-keeping, careful attention to detail and possess good time-management skills to successfully manage multiple priorities.
  • The ability to work independently and to collaborate with a multi-disciplined group in a goal- and team- oriented setting, strong interpersonal and communication skills, both written and oral
  • Analyze data, interpret results, and maintain accurate records with minimum supervision.
  • Preference given to candidates experienced in ophthalmic histological techniques.

About Us
Adverum is a clinical-stage gene therapy company targeting unmet medical needs in ophthalmology and rare diseases. Adverum develops gene therapy product candidates designed to provide durable efficacy by inducing sustained expression of a therapeutic protein. Adverum’s core capabilities include clinical development, novel vector discovery and in-house manufacturing expertise, specifically in scalable process development, assay development, and current Good Manufacturing Practices quality control.

At Adverum, Inclusion and Diversity are at our core. We believe in the power of being your authentic self.  We strive to create the space which allows for everyone in our Adverum Community to not only feel safe but encouraged to speak, learn from each other, grow in their professions and be the very best versions of themselves no matter what their age, ethnic background, gender, origin, religion or sexual orientation