Associate Scientist, In Vivo Pharmacology

Location
Philadelphia, PA
Posted
Jun 14, 2021
Ref
2529906642
Hotbed
Pharm Country
Required Education
Bachelors Degree
Position Type
Full time

Position Title: Associate Scientist, In Vivo Pharmacology

Position Level: Associate Scientist

Reports to: Scientist, In Vivo Pharmacology

 

Company Background:

Century Therapeutics is developing novel allogeneic living cell products for oncology that overcome the limitations of current cell therapies. Century’s genetically-engineered, universal iPSC-derived immune effector cell products are designed to specifically target hematologic and solid tumor cancers. Our commitment to developing off-the-shelf cell therapies will expand patient access and provide an unparalleled opportunity to advance the course of cancer care. 

 

Century’s foundational technology is built on induced pluripotent stem cells (iPSCs) that have unlimited self-renewing capacity. This enables complex cellular engineering to produce controlled cell banks of modified cells that can be expanded and differentiated into desired immune effector cells, which can supply vast amounts of allogeneic, homogeneous therapeutic products. This platform differentiates Century from other approaches that utilize non-renewable donor-derived cells.

 

Role:

The Associate Scientist, In Vivo Pharmacology, will collaborate with Century’s diverse research team to support the development of immune effector cell therapies for cancer research. We are looking for a highly motivated and organized Associate Scientist, with expertise in oncology in vivo models. His/her responsibilities include the execution of in vivo studies for the validation and characterization of targets and cellular therapies in tumor biology. The ideal candidate will work closely with scientists within the group and collaborate with members of various functional groups to achieve company aligned goals.

 

Responsibilities:

  • Execute oncology in vivo studies, in accordance with Institutional Animal Care and Use protocols
  • Analyze and document data and results
  • Manage multiple experiments simultaneously, with high attention to detail and study design, while maintaining flexibility and commitment to timelines
  • Outstanding collaborative and communication skills

 

Qualifications:

  • Bachelor’s degree in a biological sciences field with 4-6 years of relevant experience; Master’s degree in a biological sciences field with 2-4 years of relevant experience

 

Requirements:

  • Experience with rodent tumor measurements, dosing, and health monitoring is required
  • Oncology-specific in vivo pharmacology experience is required
  • Proven ability to perform hands-on techniques in rodents is required
  • Theoretical knowledge of ex vivo analysis endpoints and methodology, including flow cytometry and qPCR is preferred
  • Clear verbal and written communication is required
  • Excellent interpersonal skills with the ability to interact effectively with people and teams, internally and externally is required
  • Small animal bioluminescent/fluorescent imaging experience is preferred