Senior Manager, IT Infrastructure

San Francisco, CA, United States
Jun 11, 2021
Biotech Bay
Required Education
Bachelors Degree
Position Type
Full time

Position Summary:

The primary responsibilities of the Senior Manager, IT Infrastructure will include administration of the following: Active Directory; Office 365, including Exchange Online and SharePoint Online; Okta single sign-on; Box file services; Microsoft SCCM; AirWatch; and RingCentral/Zoom.

GBT will be adding many new SaaS apps as we move toward commercialization, and we are looking for an exceptional individual to move the IT infrastructure forward in support of that goal.

Essential Duties and Responsibilities:

  • Ensuring that best practices are applied in support of GBT's Active Directory and Office 365 implementation, including Exchange Online and SharePoint Online
  • Maintenance of Okta infrastructure, including the addition of new SaaS applications
  • Provide assistance to GBT's managed services provider, who is responsible for infrastructure monitoring and management. To include, but not limited to: Windows and Linux servers, storage, firewalls, network switches, wireless network, VMWare, and backups.
  • Supporting GBT's Box environment, including migration of existing file repositories
  • Administration of SCCM system to ensure that corporate laptops and desktops have appropriate security patches.
  • Administration of GBT's mobile device management system for corporate and BYOD devices
  • Administration of endpoint security and email security systems
  • Administration of RingCentral unified communication system and Zoom conferencing system
  • Implementation of disaster recovery policies and procedures
  • Providing second level support for help desk issues. When necessary, provide assistance with first level issues
  • Production of policy and procedure documents to support compliance initiatives
  • Must be available to participate in off-hours escalation rotation


  • BA/BS in computer science, management information systems, or an equivalent combination of education and experience that demonstrates analytical skills, problem solving, initiative, judgment, decision making and writing ability
  • 8+ years of experience supporting computer systems on a wide variety of platforms
  • Expert knowledge of Active Directory and Group Policy Objects
  • Experience with Windows, Exchange and SharePoint in a production environment
  • Proficiency with Microsoft SCCM for patching and application deployment
  • Experience with AirWatch MDM
  • Experience with AWS or Azure
  • Experience with BitLocker and MBAM
  • Proficiency with layer 3 switches, including VLAN configuration and subnet routing
  • Experience with enterprise backup systems
  • Understanding of single sign-on technology
  • Comprehensive knowledge of computer security concepts and best practices
  • Strong troubleshooting and analytical skills
  • Experience with writing shell scripts to automate tasks
  • Strong interpersonal and customer service skills
  • Must be motivated, resourceful and creative, and excited to work hard in a fast-paced environment
  • Experience with hard drive encryption implementation is desired
  • Biopharma industry experience is a plus

Fit with GBT culture:

  • Ability to build strong relationships with co-workers of various backgrounds and expertise
  • Ability to function at a high level in a team setting whether leading the group or acting as an individual contributor
  • Values-based leadership consistent with GBT's Core Values
  • Excitement about the vision and mission of GBT
  • Flexibility
  • Integrity

NOTE: This position summary is not intended to be all-inclusive. Employee may perform other related duties as negotiated to meet the ongoing needs of the organization.

Global Blood Therapeutics is an equal opportunity employer, and all qualified applicants will receive consideration for employment without regard to age, race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, or disability status, or any other characteristic protected by law.