Associate Director/Director, Head of the Development Testing Center

Location
Redwood City, CA
Posted
Jun 09, 2021
Hotbed
Biotech Bay
Required Education
Associate Degree
Position Type
Full time
Adverum is looking for an Associate Director / Director, Head of the Development Testing Center (DTC) to join the Technology Development (TechDev) team at our Redwood City, CA office.  This position reports directly into the VP of TechDev and will play a key leadership role to help advance Adverum’s lead program, ADVM-022, to commercial launch and our pipeline products into and through the clinic.  The incumbent will be responsible for developing, implementing, and then executing upon the operational vision of the DTC to support the various departments of TechDev team.
 
In this role, the incumbent will be responsible for organizing and developing the DTC team which is responsible for the high throughput / high efficiency optimization, implementation and execution of analytical assays in support of other TechDev departments.  Optimization and testing efforts will be focused on assays for AAV products, baculovirus, and several cell types.  As such, the incumbent will be expected to have a strong technical background knowledge of various analytical techniques applicable to biologic products, including ELSIA, biophysical/biochemical, chromatographic and cellular based assays.  A strong working partnership with peers in the other TechDev groups (MSAT, Process Development and Candidate Process Development), Analytical Development, Quality Control and Program Management will be key.  In addition, the ability of the incumbent to develop, motivate, and align a diverse team of scientists and engineers working on numerous projects will be vital to ensure the flexibility, efficiency, and success of the team. 
 
This role requires strong, lead-by-example orientated leadership skills, a collaborative Team focus, the ability to juggle immediate needs with long term goals, and an ability to implement organizational structure to a dynamic, growing environment. The incumbent is expected to be well versed in high throughput testing environments, and experienced with managing groups in Quality Control and/or Assay Development settings.  Direct prior experience with AAV analytics is a plus.
What you'll do
  • Working with the VP of TechDev and Head of Assay Development to set up the DTC laboratory and staff the DTC laboratory.
  • Exhibit strong leadership and managerial skills, supervise a group of up to 15 Analysts and 4 operational leaders.
  • Develop processes for managing laboratory documentation for non-GMP governance and critical reagents.
  • Be accountable for all laboratory operations for the DTC and for managing the capacity model for the DTC per requirements presented by the TechDev team.
  • Provide oversight of external testing laboratory activities including management of analytical testing, data review, troubleshooting, method improvement, generation of reports, and technical support where needed.
  • Author, review and sign off on appropriate protocols, transferred SOPs and testing reports
  • Collaborate with fellow peers in Analytical Development and Quality Control.
  • Mentor, develop and support a passionate team of individuals focused on high performance.

About you
  • PhD in Biochemistry, Chemical Engineering, Biology or related technical discipline with 7+ years of relevant, industrial experience (M.S./B.S. in corresponding fields with 12+ yrs).
  • A strong scientific track record with experience leading independent research with the ability to train and mentor research associates.
  • Experience managing a team of managers and analysts in a laboratory setting.
  • Prior experience and expertise working with biologics based analytics is a must.  A solid understanding of AAV biology and/or AAV analytics is a plus.
  • A collaborative, team-oriented mindset, able to solves problems in a goal-focused fashion with capacity to coordinate tasks across multiple projects.
  • Excellent communication, presentation, interpersonal and influencing skills across levels/disciplines.
  • Desire to build synergistic and collaborative teams with an emphasis on building and supporting a strong company culture.
  • Desire to mentor and develop members of their team.    

About Us
Adverum is a clinical-stage gene therapy company targeting unmet medical needs in ophthalmology and rare diseases. Adverum develops gene therapy product candidates designed to provide durable efficacy by inducing sustained expression of a therapeutic protein. Adverum’s core capabilities include clinical development, novel vector discovery and in-house manufacturing expertise, specifically in scalable process development, assay development, and current Good Manufacturing Practices quality control.

At Adverum, Inclusion and Diversity are at our core. We believe in the power of being your authentic self.  We strive to create the space which allows for everyone in our Adverum Community to not only feel safe but encouraged to speak, learn from each other, grow in their professions and be the very best versions of themselves no matter what their age, ethnic background, gender, origin, religion or sexual orientation