Senior Associate Scientist or Research Scientist Protein Therapeutics

Senior Associate Scientist or Research Scientist Protein Therapeutics
United States - California - Foster City

Gilead Sciences, Inc. is a research-based bio-pharmaceutical company that discovers, develops and commercializes innovative medicines in areas of unmet medical need. With each new discovery and investigational drug candidate, we seek to improve the care of patients living with life-threatening diseases around the world. Gilead's therapeutic areas of focus include HIV/AIDS, liver diseases, cancer and inflammation, and serious respiratory and cardiovascular conditions.

Making an impact on a global scale
Inclusion is one of the company's five core values. That's because we know that we are stronger and more innovative at Gilead when we are informed by a diverse set of backgrounds, experiences and points of view. Gilead Sciences is a biopharmaceutical company that discovers, develops and commercializes innovative therapeutics in areas of unmet medical need. The company's mission is to advance the care of patients suffering from life-threatening diseases worldwide.

When you join Gilead, you join our mission to change the world by enabling people to live healthier and more fulfilling lives. Come join a mission-driven bio-pharmaceutical organization that values inclusion and diversity, has a strong portfolio of products, and is constantly #CreatingPossible

Gilead is a research-based biopharmaceutical company that discovers, develops and commercializes innovative medicines in areas of unmet medical need. With each new discovery and investigational drug candidate, we seek to improve the care of patients living with life-threatening diseases around the world.

Specific Responsibilities:

The Protein Therapeutics department is responsible for the discovery, engineering, and optimization of biologic drug candidates. We seek a highly motivated individual with experience in antibody discovery and engineering. The successful candidate will work on cross-functional teams and will be a part of a functional area specializing in the discovery, engineering, and screening of novel biologic modalities across several therapeutic areas.

Essential Duties and Job Functions:

In this laboratory-based role, the successful candidate will lead engineering efforts to generate novel protein therapeutics. They should have a strong knowledge of antibody structure and function with experience in the design and engineering of new protein therapeutic modalities. The successful candidate will implement protein-protein binding and functional screening workflows to characterize leads from antibody discovery and engineering efforts. Additional job requirements:

• Work cross-functionally and across therapeutic areas to independently carry out antibody screening, engineering, and lead profiling studies
• Independently design experiments to characterize the binding and functional properties of novel antibodies
• Must have excellent presentation skills with an ability to communicate ideas and experimental findings to diverse audiences
• Maintain familiarity with scientific literature and independently apply new ideas to the development of new protein therapeutic modalities
• May represent functional area on project teams

Knowledge, Experience and Skills:

B.S./M.S. in molecular biology, biochemistry, or related field with 10+ years of additional experience in an industrial setting and a proven track record of successful antibody discovery and engineering in the form of high impact publications and/or patents. Job title is flexible based on experience. An ideal candidate will have experience in most of the following areas:

• Familiarity with molecular biology, cloning, expression, and protein purification
• Knowledge of antibody structure/function relationships and experience designing novel antibody/fusion protein constructs
• Prior experience working with antibodies and an ability to analyze antibody sequences from discovery campaigns
• Experience with biochemical assays and quantitative analysis of protein-protein binding interactions (e.g. FACS, ELISA, HTRF, Octet, etc)
• Experience with mammalian cell culture and cell-based functional assays (e.g. signaling/reporter assays, killing assays, flow cytometry, etc)
• Experience with high-throughput liquid handling systems is a plus (e.g. Biomek, etc)

Gilead Sciences is continuing to hire for all open roles. Our interview process may be conducted virtually, and some roles will be asked to temporarily work from home. Over the coming weeks and months, we will be implementing a phased approach to bringing employees back to site to ensure the health and safety of our teams.

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As an equal opportunity employer, Gilead Sciences Inc. is committed to a diverse workforce. Employment decisions regarding recruitment and selection will be made without discrimination based on race, color, religion, national origin, gender, age, sexual orientation, physical or mental disability, genetic information or characteristic, gender identity and expression, veteran status, or other non-job related characteristics or other prohibited grounds specified in applicable federal, state and local laws. In order to ensure reasonable accommodation for individuals protected by Section 503 of the Rehabilitation Act of 1973, the Vietnam Era Veterans' Readjustment Act of 1974, and Title I of the Americans with Disabilities Act of 1990, applicants who require accommodation in the job application process may contact careers@gilead.com for assistance.

For more information about equal employment opportunity protections, please view the 'EEO is the Law' poster.

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Our environment respects individual differences and recognizes each employee as an integral member of our company. Our workforce reflects these values and celebrates the individuals who make up our growing team.

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