Process Development Scientist - High-Throughput Experimentation (Synthetics)

HOW MIGHT YOU DEFY IMAGINATION?

Youve earned your degree. How will you use that achievement to reach your goals? Do more with the knowledge youve worked hard to acquire and the passion you already have. At Amgen, our shared missionto serve patientsdrives all that we do. It is key to our becoming one of the worlds leading biotechnology companies, reaching over 10 million patients worldwide. Become the professional you are meant to be in this meaningful role.

Live

What you will do

Lets do this! Lets change the world!

Amgens Process Development (PD) organization is seeking a highly motivated and creative scientist to join our newly formed High-Throughput Experimentation (HTE) team at Thousand Oaks, CA. HTE team members are responsible for accelerating scientific innovation and advancing the synthetics pipeline through rapid, automated parallel experimentation.

The successful candidate will utilize automation and HTE to support a range of process development activities, from route scouting to route optimization to process characterization, and will work cross-functionally with medicinal chemists, process chemists, chemical engineers, and analytical chemists to advance Amgens synthetic portfolio. They will also drive the development of innovative technologies and be a champion for technology and automation in the process development organization.

Scientific/Technical Responsibilities

• Collaborate with chemists and engineers to solve chemistry and process challenges using high-throughput technology and automation.

• Independently design, execute, and interpret high-throughput experiments for a variety of HTE workflows such as reaction optimization, extraction, solubility, and crystallization.

• Actively contribute to drug substance development teams by providing project updates, data interpretation, and technical recommendations.

• Identify and advance opportunities to utilize HTE to accelerate pharmaceutical development.

• Establish new workflows using automation equipment, such as automated solid/liquid handlers and high-throughput analytical systems.

• Maintain and troubleshoot automation systems and develop new protocols.

• Evaluate novel technologies that can enhance pre-existing HTE workflows and/or introduce new capabilities.

• Serve as a subject matter expert (SME) for HTE by staying current on advancements in high-throughput technology and applications in synthetic chemistry.

• Expands the capabilities of the department and resolves scientific/technical challenges.

• Collaborates with scientists and professionals outside the department.

• Provides training to PD staff on equipment and software usage.

Win

What we expect of you

We are all different, yet we all use our unique contributions to serve patients. The vital attribute professional we seek will have these qualifications.

Basic Qualifications

Doctorate degree or Doctorate degree by 2022

OR

Masters degree and 4 years of scientific experience

OR

Bachelors degree and 6 years of scientific experience

Preferred Qualifications

• Doctorate degree in Organic Chemistry, Medicinal Chemistry or Synthetic Chemistry

• Post-doctoral research experience

• Track record of demonstrated scientific accomplishments in the field of organic chemistry

• Works effectively in a multi-disciplinary team of chemists, engineers and attribute scientists

• A broad knowledge of organic synthesis is essential, including familiarity with latest developments in the fields of catalysis, photochemistry, electrochemistry, and C-H activation

• Experience with high-throughput automation systems (e.g., Unchained Labs, Andrew Alliance, Chronect, etc.) and data visualization software (e.g., Spotfire) is preferred

• Strong organizational and interpersonal skills

• Strong analytical and problem-solving skills

• Ability to champion new technologies

• Be able to maintain a productive lab presence

• Familiarity with Environmental Health and Safety expectations for chemical laboratories

• Experience in analytical techniques such as NMR, HPLC, GC, and MS is preferred

• Knowledge of basic office and chemistry software including Microsoft Word, Excel, PowerPoint, ChemDraw, and SciFinder

Thrive

Some of the vast rewards of working here

As we work to develop treatments that take care of others, so we work to care for our teammates professional and personal growth and well-being.

• Full support and career-development resources to expand your skills, enhance your expertise, and maximize your potential along your career journey

• A diverse and inclusive community of belonging, where teammates are empowered to bring ideas to the table and act

• Generous Total Rewards Plancomprising health, finance and wealth, work/life balance, and career benefitswith compensation and benefits rated above 4 stars (out of 5) on Glassdoor

Apply now

for a career that defies imagination

Objects in your future are closer than they appear. Join us.

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Equal Opportunity Statement

Amgen is an Equal Opportunity employer and will consider you without regard to your race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, or disability status.

We will ensure that individuals with disabilities are provided a reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. Please contact us to request an accommodation.

Join Us

If you're seeking a career where you can truly make a difference in the lives of others, a career where you can work at the absolute forefront of biotechnology with the top minds in the field, you'll find it at Amgen.

Amgen, a biotechnology pioneer, discovers, develops and delivers innovative human therapeutics. Our medicines have helped millions of patients in the fight against cancer, kidney disease, rheumatoid arthritis and other serious illnesses.

As an organization dedicated to improving the quality of life for people around the world, Amgen fosters an inclusive environment of diverse, ethical, committed and highly accomplished people who respect each other but compete intensely to win. Together, we live the Amgen values as we continue advancing science to serve patients.

Amgen is an Equal Opportunity employer and will consider all qualified applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, or disability status.