Associate Scientist (Immuno-Oncology)

Location
Tarrytown, New York, United States of America
Posted
Jun 05, 2021
Ref
25235BR
Required Education
Doctorate/PHD/MD
Position Type
Full time
We are seeking an Associate Scientist to join the Oncology team. The successful candidate will lead and directly contribute to the discovery / validation of novel immune-oncology targets and investigate their mechanisms of action. This candidate is expected to utilize or develop appropriate animal models, perform in vivo tumor studies and ex vivo / in vitro immune cell-based assays to characterize and screen drug candidates to support the development of immuno-therapeutics. We need an individual with a strong background in cancer immunology, myeloide cell biology and possess excellent interpersonal and communication skills to work in the highly collaborative, fast-paced and dynamic environment.

As an Associate Scientist in Oncology, a typical day may include the following:

- Be a critical thinker familiar with recent developments in the field. Develop in-depth scientific knowledge in the area of research focus, be able to rationalize and nominate new drug targets based on external and internal data and contribute to the decision making on project direction.
- Plan, design, and independently perform advanced in vivo tumor studies in mice: tumor implantation / measurement, dosing, bleeding and dissection of tumors and immune organs for subsequent ex vivo / in vitro analysis
- Design, perform and analyze multi color flow cytometry (FACS) experiments on human and murine cells, tumors, and tissues
- Peform IHC/IF/RNAscope stains and analysis
- Develop cell-based functional assays using engineered and/or primary human and murine cells
- Maintain complete, accurate, and timely record of experiments and data analysis
- Summarize results across experiments and programs in presentations to colleagues on the team, across departments, and senior management with scientific rigor
- Responsible for authoring documents to be published in regulatory filings, patent applications, external conference posters, and journal articles

This role may be for you if:

- You have strong organizational and time-management skills including the ability to handle multiple tasks/projects simultaneously
- You demonstrate creativity and independence
- You are able to effectively collaborate within cross-functional teams
- You have clear and professional verbal and written communication

To be considered for this role, you must have a Ph.D. in immunology or a related field with 0-3 years of post-doctoral experience in academia or industry. Master sterile cell culture techniques required for cell lines and primary human and murine cells. We are seeking expertise with animal handling, different methods of compound administration (i.v., i.p., s.c., etc), bleeding, and tissue /sample collection. Must be skillful in the isolation and characterization of primary immune cells from murine tissues/tumors and human blood. Excellent skill set for a variety of in vitro/ex vivo immune cell-based assays, including planning, execution, and analysis. We need a candidate who is skilled in flow cytometry panel design and practical experience with advanced flow cytometry, including cell surface staining, intracellular staining, data acquisition and analysis. Experience with IHC or IF or RNAscope staining including data analysis (Experience using analysis software ImageJ or HALO is advantageous).

Does this sound like you? Apply now to take your first steps toward living the Regeneron Way! We have an inclusive and diverse culture that provides amazing benefits including health and wellness programs, fitness centers and stock for employees at all levels!

Regeneron is an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion or belief (or lack thereof), sex, nationality, national or ethnic origin, civil status, age, citizenship status, membership of the Traveler community, sexual orientation, disability, genetic information, familial status, marital or registered civil partnership status, pregnancy or maternity status, gender identity, gender reassignment, military or veteran status, or any other protected characteristic in accordance with applicable laws and regulations. We will ensure that individuals with disabilities are provided reasonable accommodations to participate in the job application process. Please contact us to discuss any accommodations you think you may need.