R&D Associate (Immuno-Oncology)

Location
Tarrytown, NY, United States
Posted
Jun 05, 2021
Ref
25157BR
Required Education
Associate Degree
Position Type
Full time
We are seeking a highly motivated R&D Associate to join the Immuno-Oncology team at Regeneron Pharmaceuticals as we make transformational advances in harnessing the power of the immune system to fight cancer. The position will involve using complex histological and pharmacodynamic studies to reveal potential target expression and investigate the mechanism of action of novel immuno-oncology therapeutics. This role will be deeply involved in the development of cutting edge therapeutics including bispecific antibodies, antibody-drug conjugates and CAR-T cells. You will work closely with other team members and collaborators to advance programs spanning from initial target discovery to support of ongoing clinical stage therapeutics.

As an R&D Associate, a typical day may include the following:
• Expertise in the independent execution of large and sophisticated immunohistochemistry (IHC) assays, including the use of high-throughput Ventana and Leica autostainer platforms.
• Fluency in RNA in-situ hybridization (ISH) based assays and familiarity with modern platforms such as RNAscope.
• Proficiency in histological tissue processing, microtomy, cryosectioning and H&E staining of human and non-human tissues.
• Practice in the development and characterization of novel antibodies and probes for IHC and ISH assays.
• Scanning of slides and assembly of images in PowerPoint and other formats for presentation.
• Basic analysis of images and frequent collaboration with members of Pathology.
• Competency in cell culture, multi-parameter flow cytometry and ELISA based assays.
• Comfort with in vivo animal studies and proficiency in the processing of tumors, normal tissues and blood for subsequent assays such as flow cytometry.

This role may be for you if:
• You have proven basic histology skills and a desire to further expand and develop your skill set and knowledge of the immuno-oncology drug development process.
• You are enthusiastic to learn new skill sets including multiplex IHC, performing cell culture and multi-parameter flow cytometry and ELISA based assays.
• You are detail-oriented, have strong time management skills and appreciate an opportunity for growth as a scientist.
• You possess the drive and desire to learn how to troubleshoot and think outside the box to solve complex problems.
• You have excellent written and verbal communication skills; the ability to work as part of a diverse team.

To be considered for this role, you must have an AS/BS or MS degree in a relevant scientific discipline (Immunology, Oncology, Molecular/Cell Biology) with 2-5 years laboratory experience (in academia or industry) is required. Experience in the research and development of targeted cancer therapeutics including antibodies and CAR-T cells is an advantage. In addition, the ideal candidate will have Strong organizational skills including the ability to manage and record details of several complex projects simultaneously.

Does this sound like you? Apply now to take your first steps toward living the Regeneron Way! We have an inclusive and diverse culture that provides amazing benefits including health and wellness programs, fitness centers and stock for employees at all levels!

Regeneron is an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion or belief (or lack thereof), sex, nationality, national or ethnic origin, civil status, age, citizenship status, membership of the Traveler community, sexual orientation, disability, genetic information, familial status, marital or registered civil partnership status, pregnancy or maternity status, gender identity, gender reassignment, military or veteran status, or any other protected characteristic in accordance with applicable laws and regulations. We will ensure that individuals with disabilities are provided reasonable accommodations to participate in the job application process. Please contact us to discuss any accommodations you think you may need.