Research Associate, Cell Based Assays

Location
South San Francisco, CA, United States
Posted
Jun 04, 2021
Ref
5179351002
Discipline
Science/R&D, Research
Required Education
Bachelors Degree
Position Type
Full time
JOB PURPOSE

Sana Biotechnology is looking to expand our team with creative and highly motivated individuals who believe in the potential of cells as engineered medicines, have the vision to do creative things, and the determination to execute that vision.

We are looking for a qualified research associate to help build the Analytical Development department at Sana Biotechnology. This person will join an innovative, multi-disciplinary team developing and implementing analytical methods and data analysis to support the advancement of Sana's pipeline. This position will work cross-functionally with scientists from Research, Process Development, and Quality Control to determine the appropriate methodologies to assess drug products, intermediates, and critical reagents. This is a unique opportunity to develop assays to characterize the functional attributes of gene and cell therapy products.

DUTIES AND RESPONSIBILITIES
  • Perform routine testing to support cell therapy and gene therapy process development
  • Support the development of robust analytical methods (including cell-based functional assays) for cell and gene therapy products, critical reagents and raw materials
  • Promote functional assay best practices locally and across Sana
  • Prepare test procedures, protocols and other technical documents
  • Identify and troubleshoot unusual results or instrumentation issues
  • Transfer methods to quality control and support their implementation and execution
  • Characterize gene and cell therapy products for regulatory filings and to demonstrate comparability between lots
  • Purchase and maintain analytical instrumentation and coordinate support with vendors
  • Occasional travel between Sana locations

QUALIFICATIONS

Basic Qualifications
  • BS degree in immunology, cell, molecular biology, or other life science with 1+ years of industry experience in analytical development, quality control or process development roles, or relevant research in an academic setting
  • Experience with eukaryotic cell culture and aseptic technique
  • Experience with cell-based and molecular biology techniques including ELISAs, cell-based assays, multi-color flow-based applications and/or PCR-based applications
  • Detailed record keeping and documentation of relevant experimental details
  • Ability to design thoughtful experiments, critically evaluate data, and summarize results in a meaningful way
  • Must be resourceful with respect to learning new skills, techniques, and therapeutic modalities
  • Ability to work in a high paced team environment, meet deadlines, and prioritize work from multiple projects
  • Excellent verbal and written communication skills for technical and non-technical audiences
  • Demonstrated strong critical thinking and organizational skills
  • Detail oriented, self-motivated, independent, flexible, and able to prioritize and manage several projects concurrently in a fast-paced start-up environment
  • Demonstrated ability to work in cross-functional teams as a strong team player as well as independently
  • Demonstrated ability to exhibit curiosity both with scientific rigor and relationships
  • Ability to engage in crucial conversations - providing and receiving feedback
  • Working safely in person on a predictable and regular in-person basis is an essential job function for this position and the Company requires that all individuals working in-person, subject to certain exceptions, be fully vaccinated against COVID-19.

Preferred Qualifications
  • Previous experience with automation, qPCR, ddPCR, nucleic acid preparations
  • Familiarity with various software packages used for data analysis including Jmp, GraphPad Prism
  • Occasional travel between Sana locationsThe candidate should be a team player, highly organized with excellent communication skills, demonstrate curiosity and scientific rigor and excellent problem-solving skills
  • Ability to work in a high paced team environment, meet deadlines, and prioritize work from multiple projects


To perform this job successfully, an individual must be able to perform each essential duty satisfactorily. The job description listed above is representative of the knowledge, skill, and/or ability required. Reasonable accommodations may be made to enable individuals with disabilities to perform the essential functions.

At Sana, we believe that a diverse workforce strengthens us as a company and helps us to achieve our mission to meaningfully change the outcome of many human diseases. This belief is a pillar of our business and is critical to our success. Our goal is that Sana is the place for talented people to bring their authentic selves to work, to have a great career and to deeply, positively impact patients.

The Company is committed to providing a workplace free of discrimination and harassment based on race, color, religion, age, gender, national origin, ancestry, physical or mental or sensory disability (including the use of a trained guide dog or service animal by a person with a disability), genetic information, actual or perceived HIV or Hepatitis C infection, medical condition (cancer or a record or history of cancer and genetic characteristics), marital status, sexual orientation, sexual preference, pregnancy (including childbirth and related medical conditions), disability, veteran status, political ideology, taking or requesting statutorily protected leave, status as a victim of domestic violence, sexual assault or stalking, or any other basis prohibited by applicable law.

Core to our values, we believe there is nothing more important than the health and wellness of you and your family. We cover 100% of the cost for employee health coverage and offer generous time-off, parental leave, short and long term disability, financial wellness programs, a 401(k) Plan, Employee Stock Purchase Plan, commuter subsidy and a variety of wellness offerings to support each person individually.