Staff Bioinformatics Scientist - Post-Diagnostic Applications

Menlo Park, CA, United States
Jun 04, 2021
Biotech Bay
Required Education
Bachelors Degree
Position Type
Full time
GRAIL is a healthcare company whose mission is to detect cancer early, when it can be cured. GRAIL is focused on alleviating the global burden of cancer by developing pioneering technology to detect and identify multiple deadly cancer types early. The company is using the power of next-generation sequencing, population-scale clinical studies, and state-of-the-art computer science and data science to enhance the scientific understanding of cancer biology, and to develop its multi-cancer early detection blood test. GRAIL is headquartered in Menlo Park, CA with locations in Washington, D.C., North Carolina, and the United Kingdom. It is supported by leading global investors and pharmaceutical, technology, and healthcare companies. For more information, please visit

This position is with the post-diagnosis bioinformatics and data science team within GRAIL's Bioinformatics and Data Science organization. We are establishing a team to monitor the dynamics of disease burden and to characterize disease biology with a focus on the post-diagnostic setting. We work with interdisciplinary scientists, clinicians, engineers, and external collaborators to build new diagnostic products to support pharmaceutical development and cancer patient care.

You Will:

• Lead end-to-end analyses that include data gathering, processing, analysis, iteration with stakeholders, and presentation of results.
• Demonstrate your knowledge of Bayesian statistics to craft, develop, and improve computational tools.
• Design, execute, and own analyses of large, complex genomics datasets using machine learning and statistical methods to generate biological insights.
• Interact cross-functionally and work closely with teams including software engineering, clinical, laboratory operations, research, and product development.
• Collaborate to design, analysis, and presentation of experiments with external collaborators.
• Create and communicate rigorous scientific analyses.

Your Background Includes:

• Ph.D. in Bioinformatics, Statistics, Computational Biology, Cancer Biology, Genetics, Genomics, Biological Sciences, Computer Science, Physics, or equivalent preparation and experience.
• Deep understanding of modern statistical and machine learning tools for the analysis of genomics datasets and their use in clinical test development.
• Proven ability to apply these skills to uncover new biological insights from large genomics datasets.
• Demonstrated industry expertise in at least one programming language (Go, R, Python, C++, Java, C#), experience with version control tools and reproducible research practices in a Linux environment.
• Proven track record of scientific contributions demonstrated by highly cited publications, tools, products, or data sets used in commercial products and by the scientific community, presentations at international conferences, intellectual property, and awards.
• 3-5 years relevant experience in positions of increasing responsibility
• Proven track record of design, execution and leadership of industry projects in a regulated environment, involving oncology applications, next-generation sequencing, or molecular tests.
• Self-direction, willingness to both teach others and learn new techniques.
• Effective written and verbal communication skills.

We are an equal opportunity employer and value diversity at our company. We do not discriminate on the basis of race, religion, color, national origin, gender, sexual orientation, age, marital status, veteran status, or disability status.

GRAIL, Inc. and its affiliates and subsidiaries ("GRAIL") does not accept any liability for fees for resumes from recruiters or employment agencies ("Agency"), without a binding, written recruitment agreement between GRAIL and Agency describing the services and specific job openings ("Agreement"). GRAIL may consider any candidate for whom an Agency has submitted an unsolicited resume and explicitly reserves the right to hire those candidate(s) without any financial obligation to the Agency, unless an Agreement is in place. Any email or verbal contacts with any person within GRAIL is inadequate to create a binding agreement. Agencies without an Agreement are requested not to contact any hiring managers of GRAIL with recruiting inquiries or resumes. Agencies interested in partnering with GRAIL may contact GRAIL's HR Department through our Customer Service team .