Senior Manager, IT Technology and Operations

Foster City, CA, United States
Jun 03, 2021
Biotech Bay
Required Education
Bachelors Degree
Position Type
Full time
Vaxcyte, Inc. (Nasdaq: PCVX) is a next-generation vaccine company seeking to improve global health by developing superior and novel vaccines designed to prevent some of the most common and deadly infectious diseases worldwide. Our exclusively licensed cell-free protein synthesis platform and our proprietary know how enable us to design and produce optimized protein carriers and antigens, the critical building blocks of vaccines, in ways that we believe conventional vaccine technologies cannot. Our pipeline includes pneumococcal conjugate vaccine, or PCV, candidates that we believe are the most bro ad-spectrum PCV candidates currently in development, targeting the $7 billion global pneumococcal vaccine market. Our lead vaccine candidate, VAX-24, is a preclinical, 24-valent broad-spectrum pneumococcal conjugate PCV with preclinical proof-of- concept demonstrating potential to replace the standard of care that we expect to advance into clinical trials in the second half of 2021. Our pipeline also includes VAX-XP, a PCV with an expanded breadth of coverage of at least 30 strains, including newly emerging strains responsible for invasive pneumococcal disease and antibiotic resistance; VAX-A1, a prophylactic vaccine candidate designed to prevent Group A Strep infections; and VAX-PG, a therapeutic vaccine candidate designed to slow or stop the progression of periodontal disease by targeting the keystone pathogen responsible for this chronic, oral inflammatory disease. We completed our initial public offering in June 2020, raising $287.5 million in gross proceeds.


Vaxcyte is looking for an energetic, independent and progressive technical leader to join our Information Technology team. This role is responsible for the architectural design, implementation, management and optimization of Vaxcyte's IT infrastructure and support operations. A successful candidate will interact closely, proactively and independently with IT colleagues, cross-functional project teams, key business stakeholders and 3 rd party partners to develop a largely virtual, best- in-class, scalable, and secure technology infrastructure and support team. While Vaxcyte IT maintains a "cloud-first" mentality in everything we do, a proven and collective track record in the delivery of cloud, on-premise and hybrid infrastructure solutions is required. The ideal candidate will have IT experience working in public, Life Sciences companies. While not required, IT experience in a laboratory environment is a plus. Th is position reports to the Vice President of IT and Facilities.

Essential Functions:

• Build, oversee, and optimize a best- in-class, customer-centric service desk operation.
• Design hardened, redundant and virtualized technical solutions that scale with company growth.
• Implement a highly scalable and available secure network solution for all physical spaces.
• Oversee and closely manage 3 rd party technology partner performance, including budgets.
• Help refine and evolve a rolling three-year IT strategic technology roadmap.
• Implement, monitor and maintain a consolidated technology monitoring solution.
• Define and develop metrics to monitor SLAs and ROI on technology investments.
• Deploy proven security / identity management solutions.
• Implement proven cyber-security solutions that protect across all attack vectors (office and lab).
• Achieve operational consistency, efficiency and compliance through procedures and playbooks.
• Consistently improve adoption rate of end-user productivity solutions.
• Increase employee and 3 rd party-partner engagement through the use of collaboration tools.
• Support internal and external regulatory audits when technical input is required.
• Serve as technology delivery lead for critical, enterprise initiatives.
• Lead IT infrastructure and operational qualification efforts.
• Instruct and mentor others by doing; take a hands-on approach and contribute to solutions.
• Cultivate relationships and maintain a passionate "customer first" attitude. Be proactive!


• Bachelor degree in IT-related discipline or commensurate hands-on technical experience.
• 10+ years IT experience in a regulated industry, preferably Life Sciences.
• Experience building and managing IT service desk operations.
• Experience implementing and managing ticketing systems (ServiceNow, Jira, ZenDesk).
• Admin experience in networks, firewalls, servers, databases and storage devices required.
• Understand ITIL and how to incorporate into operations framework.
• Knowledge of IT standards and requirements for laboratory instruments a definite plus.
• Solid understanding of virtualized systems, architecture and integrations.
• Demonstrated track record deploying emerging technologies in support of an elastic IT.
• Proficiency in cloud platforms such as AWS and Azure.
• Expertise with directory services and Single Sign On (SSO) identity management solutions.
• Experience with A/V, telecom and workspace productivity solutions.
• Working knowledge of enterprise business systems such as ERP, HRIS, LMS, EDMS.
• Project management and delivery methodology experience.
• Exceptional communication and meeting facilitation skills.
• Thrive in a fast-paced, results-driven, and team-oriented environment.

Reports to: Vice President of IT and Facilities

Location: Foster City, CA


The compensation package will be competitive and includes comprehensive benefits and an equity component.